LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 85.43 | 12.0 | Inf | Inf | -0.9704 | -0.7957 | 2.4990 | 1.5206 |
| MCF 10A-H2B-mCherry | Alpelisib | 49.15 | 11.9 | Inf | Inf | 0.8148 | 0.8290 | 2.4998 | 0.0068 |
| MCF 10A-H2B-mCherry | Taxol | 69.60 | 11.9 | Inf | Inf | 0.6450 | 0.3071 | 2.4999 | 0.7524 |
| MCF 10A-H2B-mCherry | Alpelisib | 16.79 | 11.9 | Inf | Inf | 0.4687 | 0.5844 | 2.5000 | 0.1607 |
| MCF 10A-H2B-mCherry | Trametinib | 18.49 | 11.9 | Inf | Inf | 0.3116 | 0.3689 | 2.5000 | 0.4518 |
| MCF 10A-H2B-mCherry | Alpelisib | 57.67 | 11.9 | Inf | Inf | 0.9066 | 0.8952 | 2.5000 | 0.0030 |
| MCF 10A-H2B-mCherry | Trametinib | 73.49 | 11.9 | Inf | Inf | -0.1619 | 0.0708 | 2.5000 | 0.4352 |
| MCF 10A-H2B-mCherry | Alpelisib | 50.86 | 11.9 | Inf | Inf | 0.8643 | 0.8641 | 2.5000 | 0.0066 |
| MCF 10A-H2B-mCherry | Alpelisib | 52.56 | 11.9 | Inf | Inf | 0.8858 | 0.8764 | 2.5000 | -0.0107 |
| MCF 10A-H2B-mCherry | Alpelisib | 54.25 | 11.9 | Inf | Inf | 0.9331 | 0.9259 | 2.5000 | -0.0161 |
| MCF 10A-H2B-mCherry | Alpelisib | 55.97 | 11.9 | Inf | Inf | 0.9301 | 0.9223 | 2.5000 | -0.0036 |
| MCF 10A-H2B-mCherry | Alpelisib | 23.60 | 11.9 | Inf | Inf | 0.5168 | 0.4975 | 2.5000 | 0.1285 |
| MCF 10A-H2B-mCherry | Alpelisib | 21.90 | 11.9 | Inf | Inf | 0.4426 | 0.4238 | 2.5000 | 0.1686 |
| MCF 10A-H2B-mCherry | Alpelisib | 20.19 | 11.9 | Inf | Inf | 0.4666 | 0.4567 | 2.5000 | 0.1534 |
| MCF 10A-H2B-mCherry | Alpelisib | 18.49 | 11.9 | Inf | Inf | 0.4464 | 0.5217 | 2.5000 | 0.1547 |
| MCF 10A-H2B-mCherry | Vorinostat | 50.86 | 11.9 | 1.6427 | 2.2275 | -0.1772 | -0.2769 | 2.5033 | 0.2296 |
| MCF 10A-H2B-mCherry | Vorinostat | 40.63 | 11.9 | 1.1841 | 1.3562 | -0.1480 | -0.1647 | 2.5578 | 0.3101 |
| MCF 10A-H2B-mCherry | Taxol | 50.86 | 11.9 | 0.0011 | 0.0014 | -0.6471 | -0.4615 | 2.5981 | 0.9039 |
| MCF 10A-H2B-mCherry | Taxol | 49.15 | 11.9 | 0.0011 | 0.0014 | -0.7087 | -0.4671 | 2.6462 | 0.8938 |
| MCF 10A-H2B-mCherry | Palbociclib | 28.71 | 11.9 | 0.1921 | 0.1743 | 0.0502 | 0.1399 | 2.7597 | 0.4197 |
| MCF 10A-H2B-mCherry | Dasatinib | 66.19 | 11.9 | 1.4145 | 4.3056 | -0.5860 | -0.9014 | 2.7702 | 0.3291 |
| MCF 10A-H2B-mCherry | Taxol | 52.56 | 11.9 | 0.0012 | 0.0016 | -0.7607 | -0.5550 | 2.7936 | 0.9382 |
| MCF 10A-H2B-mCherry | Dasatinib | 64.49 | 11.9 | 1.8515 | 4.5604 | -0.5153 | -0.8450 | 2.8465 | 0.2907 |
| MCF 10A-H2B-mCherry | Alpelisib | 35.52 | 11.9 | 17.5986 | 36.6414 | 0.6041 | -0.0856 | 2.8588 | 0.0554 |
| MCF 10A-H2B-mCherry | Vorinostat | 54.25 | 11.9 | 2.1006 | 2.42 | -0.1151 | -0.1804 | 2.8861 | 0.1820 |