LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)

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Cell Small Molecule Time Point (hr) Time Interval (hr) GR50 GEC50 GRmax GRinf GR Hill Coefficient GR_AOC
MCF 10A-H2B-mCherry Taxol 42.33 11.9
0.0009
0.0013
 -0.6426 -0.5128 2.3074 0.9302
MCF 10A-H2B-mCherry Taxol 52.56 11.9
0.0012
0.0016
 -0.7607 -0.5550 2.7936 0.9382
MCF 10A-H2B-mCherry Dasatinib 85.43 12.0
Inf
Inf
 -0.8540 -0.8540 0.0000 0.9401
MCF 10A-H2B-mCherry Taxol 57.67 11.9
0.0016
0.0019
 -0.7476 -0.6006 5.0000 0.9487
MCF 10A-H2B-mCherry Taxol 66.19 11.9
0.0015
0.0018
 -0.7264 -0.5641 5.0000 0.9534
MCF 10A-H2B-mCherry Dasatinib 85.43 11.9
Inf
Inf
 -0.9117 -0.9117 0.0000 0.9543
MCF 10A-H2B-mCherry Etoposide 73.49 11.9
Inf
Inf
 -0.6007 -0.6007 0.0000 0.9782
MCF 10A-H2B-mCherry Taxol 73.49 11.9
Inf
Inf
 -0.8372 -0.6518 0.5709 1.0513
MCF 10A-H2B-mCherry Alpelisib 89.69 11.9
Inf
Inf
 -0.9954 -0.9954 0.0000 1.0518
MCF 10A-H2B-mCherry Etoposide 76.90 11.9
Inf
Inf
 -0.8928 -0.8928 0.0000 1.0768
MCF 10A-H2B-mCherry Dasatinib 89.69 11.9
Inf
Inf
 -0.9466 -0.9466 0.0000 1.1164
MCF 10A-H2B-mCherry Etoposide 80.31 11.9
Inf
Inf
 -0.9514 -0.9514 0.0000 1.1514
MCF 10A-H2B-mCherry Etoposide 85.43 11.9
Inf
Inf
 -0.8878 -0.8878 0.0000 1.1597
MCF 10A-H2B-mCherry Etoposide 85.43 12.0
Inf
Inf
 -0.8811 -0.8811 0.0000 1.1884
MCF 10A-H2B-mCherry Taxol 76.90 11.9
0.0001
0.0003
 -0.9743 -0.6652 0.7092 1.2470
MCF 10A-H2B-mCherry Etoposide 89.69 11.9
Inf
Inf
 -0.7330 -0.7330 0.0000 1.3084
MCF 10A-H2B-mCherry Taxol 80.31 11.9
0.0
0.0002
 -1.0000 -0.8852 0.6794 1.4491
MCF 10A-H2B-mCherry Taxol 85.43 12.0
Inf
Inf
 -0.9704 -0.7957 2.4990 1.5206
MCF 10A-H2B-mCherry Taxol 85.43 11.9
Inf
Inf
 -0.9909 -0.8242 2.4551 1.5351
MCF 10A-H2B-mCherry Taxol 89.69 11.9
0.0001
0.0001
 -0.3321 -0.7000 4.9958 1.5687