LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Dasatinib | 85.43 | 12.0 | Inf | Inf | -0.8540 | -0.8540 | 0.0000 | 0.9401 |
| MCF 10A-H2B-mCherry | Dasatinib | 89.69 | 11.9 | Inf | Inf | -0.9466 | -0.9466 | 0.0000 | 1.1164 |
| MCF 10A-H2B-mCherry | Etoposide | 15.08 | 11.9 | Inf | Inf | 0.0410 | -0.3362 | 0.4618 | 0.2363 |
| MCF 10A-H2B-mCherry | Etoposide | 71.30 | 11.9 | Inf | Inf | -0.6076 | -0.5220 | 0.7739 | 0.7550 |
| MCF 10A-H2B-mCherry | Etoposide | 73.49 | 11.9 | Inf | Inf | -0.6007 | -0.6007 | 0.0000 | 0.9782 |
| MCF 10A-H2B-mCherry | Etoposide | 76.90 | 11.9 | Inf | Inf | -0.8928 | -0.8928 | 0.0000 | 1.0768 |
| MCF 10A-H2B-mCherry | Etoposide | 80.31 | 11.9 | Inf | Inf | -0.9514 | -0.9514 | 0.0000 | 1.1514 |
| MCF 10A-H2B-mCherry | Etoposide | 85.43 | 11.9 | Inf | Inf | -0.8878 | -0.8878 | 0.0000 | 1.1597 |
| MCF 10A-H2B-mCherry | Etoposide | 85.43 | 12.0 | Inf | Inf | -0.8811 | -0.8811 | 0.0000 | 1.1884 |
| MCF 10A-H2B-mCherry | Etoposide | 89.69 | 11.9 | Inf | Inf | -0.7330 | -0.7330 | 0.0000 | 1.3084 |
| MCF 10A-H2B-mCherry | Neratinib | 71.30 | 11.9 | Inf | Inf | -0.7067 | -0.7067 | 0.0000 | 0.3198 |
| MCF 10A-H2B-mCherry | Neratinib | 73.49 | 11.9 | Inf | Inf | -1.0000 | -1.0000 | 0.0000 | 0.4286 |
| MCF 10A-H2B-mCherry | Neratinib | 76.90 | 11.9 | Inf | Inf | -1.0000 | -1.0000 | 0.0000 | 0.3500 |
| MCF 10A-H2B-mCherry | Neratinib | 80.31 | 11.9 | Inf | Inf | -1.0000 | -1.0000 | 0.0000 | 0.3828 |
| MCF 10A-H2B-mCherry | Neratinib | 85.43 | 11.9 | Inf | Inf | 0.1308 | 0.1308 | 0.0000 | 0.4931 |
| MCF 10A-H2B-mCherry | Neratinib | 85.43 | 12.0 | Inf | Inf | -0.8789 | -0.8789 | 0.0000 | 0.5982 |
| MCF 10A-H2B-mCherry | Neratinib | 89.69 | 11.9 | Inf | Inf | 1.0500 | 1.0500 | 0.0000 | 0.5370 |
| MCF 10A-H2B-mCherry | Palbociclib | 15.08 | 11.9 | Inf | Inf | 0.1532 | 0.1532 | 0.0000 | 0.4065 |
| MCF 10A-H2B-mCherry | Palbociclib | 16.79 | 11.9 | Inf | Inf | 0.1194 | -0.3957 | 0.0878 | 0.4436 |
| MCF 10A-H2B-mCherry | Palbociclib | 18.49 | 11.9 | Inf | Inf | 0.0520 | -0.4305 | 0.1045 | 0.4625 |
| MCF 10A-H2B-mCherry | Palbociclib | 69.60 | 11.9 | Inf | Inf | -0.4255 | -0.5524 | 1.2035 | 0.1809 |
| MCF 10A-H2B-mCherry | Palbociclib | 71.30 | 11.9 | Inf | Inf | -0.2922 | -0.3418 | 1.3773 | 0.1777 |
| MCF 10A-H2B-mCherry | Palbociclib | 85.43 | 11.9 | Inf | Inf | -0.9917 | -0.9933 | 0.6160 | 0.5482 |
| MCF 10A-H2B-mCherry | Palbociclib | 85.43 | 12.0 | Inf | Inf | -0.9908 | -0.9912 | 0.5687 | 0.5120 |
| MCF 10A-H2B-mCherry | Palbociclib | 89.69 | 11.9 | Inf | Inf | -0.9796 | -0.9796 | 0.0000 | 0.6834 |