LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)

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Cell Small Molecule Time Point (hr) Time Interval (hr) GR50 GEC50 GRmax GRinf GR Hill Coefficient GR_AOC
MCF 10A-H2B-mCherry Taxol 69.60 11.9
Inf
Inf
 0.6450 0.3071 2.4999 0.7524
MCF 10A-H2B-mCherry Taxol 73.49 11.9
Inf
Inf
 -0.8372 -0.6518 0.5709 1.0513
MCF 10A-H2B-mCherry Taxol 85.43 11.9
Inf
Inf
 -0.9909 -0.8242 2.4551 1.5351
MCF 10A-H2B-mCherry Taxol 85.43 12.0
Inf
Inf
 -0.9704 -0.7957 2.4990 1.5206
MCF 10A-H2B-mCherry Trametinib 15.08 11.9
Inf
Inf
 0.3411 0.3411 0.0000 0.3691
MCF 10A-H2B-mCherry Trametinib 16.79 11.9
Inf
Inf
 0.4137 0.4380 0.6914 0.4102
MCF 10A-H2B-mCherry Trametinib 18.49 11.9
Inf
Inf
 0.3116 0.3689 2.5000 0.4518
MCF 10A-H2B-mCherry Trametinib 73.49 11.9
Inf
Inf
 -0.1619 0.0708 2.5000 0.4352
MCF 10A-H2B-mCherry Trametinib 76.90 11.9
Inf
Inf
 0.2209 0.2209 0.0000 0.3859
MCF 10A-H2B-mCherry Trametinib 80.31 11.9
Inf
Inf
 0.1537 0.1537 0.0000 0.4652
MCF 10A-H2B-mCherry Trametinib 85.43 11.9
Inf
Inf
 0.0455 0.0455 0.0000 0.6300
MCF 10A-H2B-mCherry Trametinib 85.43 12.0
Inf
Inf
 0.0802 0.0802 0.0000 0.6023
MCF 10A-H2B-mCherry Trametinib 89.69 11.9
Inf
Inf
 -0.1007 -0.1007 0.0000 0.7813
MCF 10A-H2B-mCherry Vorinostat 71.30 11.9
Inf
Inf
 0.0118 0.0118 0.0000 0.1999
MCF 10A-H2B-mCherry Vorinostat 73.49 11.9
Inf
Inf
 -0.1017 -0.1017 0.0000 0.3738
MCF 10A-H2B-mCherry Vorinostat 76.90 11.9
Inf
Inf
 -0.0732 -0.0732 0.0000 0.4695
MCF 10A-H2B-mCherry Vorinostat 80.31 11.9
Inf
Inf
 -0.0761 -0.0761 0.0000 0.6257
MCF 10A-H2B-mCherry Vorinostat 85.43 11.9
Inf
Inf
 0.1827 0.1827 0.0000 0.6413
MCF 10A-H2B-mCherry Vorinostat 85.43 12.0
Inf
Inf
 0.1293 0.1293 0.0000 0.6446
MCF 10A-H2B-mCherry Alpelisib 15.08 11.9
Inf
Inf
 0.4895 0.4895 0.0000 0.1563