LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Dasatinib | 59.37 | 11.9 | 4.4684 | 6.0639 | -0.4145 | -0.7730 | 5.0000 | 0.2216 |
| MCF 10A-H2B-mCherry | Dasatinib | 32.11 | 11.9 | 0.3734 | 6.0886 | 0.0171 | -0.4728 | 0.5261 | 0.3838 |
| MCF 10A-H2B-mCherry | Etoposide | 20.19 | 11.9 | 1.0484 | 6.2551 | 0.0379 | -0.5651 | 0.6316 | 0.2770 |
| MCF 10A-H2B-mCherry | Alpelisib | 38.93 | 11.9 | Inf | 6.4483 | 0.6837 | 0.6427 | 5.0000 | 0.0115 |
| MCF 10A-H2B-mCherry | Dasatinib | 55.97 | 11.9 | 4.1363 | 6.7932 | -0.4294 | -1.0000 | 3.3320 | 0.2248 |
| MCF 10A-H2B-mCherry | Alpelisib | 40.63 | 11.9 | Inf | 7.2456 | 0.7345 | 0.6596 | 5.0000 | 0.0088 |
| MCF 10A-H2B-mCherry | Palbociclib | 61.08 | 11.9 | 2.1041 | 7.3693 | -0.0875 | -0.6827 | 1.3243 | 0.2108 |
| MCF 10A-H2B-mCherry | Palbociclib | 59.37 | 11.9 | 1.8094 | 7.7655 | -0.1104 | -0.8492 | 0.8174 | 0.2344 |
| MCF 10A-H2B-mCherry | Dasatinib | 54.25 | 11.9 | 2.4281 | 8.3283 | -0.3369 | -1.0000 | 1.0304 | 0.2327 |
| MCF 10A-H2B-mCherry | Dasatinib | 52.56 | 11.9 | 1.4789 | 9.4423 | -0.2797 | -1.0000 | 0.6283 | 0.2800 |
| MCF 10A-H2B-mCherry | Vorinostat | 89.69 | 11.9 | Inf | Inf | 0.5920 | 0.5920 | 0.0000 | 0.6243 |
| MCF 10A-H2B-mCherry | Alpelisib | 16.79 | 11.9 | Inf | Inf | 0.4687 | 0.5844 | 2.5000 | 0.1607 |
| MCF 10A-H2B-mCherry | Alpelisib | 18.49 | 11.9 | Inf | Inf | 0.4464 | 0.5217 | 2.5000 | 0.1547 |
| MCF 10A-H2B-mCherry | Alpelisib | 20.19 | 11.9 | Inf | Inf | 0.4666 | 0.4567 | 2.5000 | 0.1534 |
| MCF 10A-H2B-mCherry | Alpelisib | 21.90 | 11.9 | Inf | Inf | 0.4426 | 0.4238 | 2.5000 | 0.1686 |
| MCF 10A-H2B-mCherry | Alpelisib | 23.60 | 11.9 | Inf | Inf | 0.5168 | 0.4975 | 2.5000 | 0.1285 |
| MCF 10A-H2B-mCherry | Alpelisib | 27.00 | 11.9 | Inf | Inf | 0.6407 | 0.6557 | 0.5188 | 0.0807 |
| MCF 10A-H2B-mCherry | Alpelisib | 44.03 | 11.9 | Inf | Inf | 0.8013 | -0.0883 | 0.3719 | 0.0392 |
| MCF 10A-H2B-mCherry | Alpelisib | 45.74 | 11.9 | Inf | Inf | 0.8089 | 0.1521 | 0.3040 | 0.0556 |
| MCF 10A-H2B-mCherry | Alpelisib | 47.45 | 11.9 | Inf | Inf | 0.7990 | 0.8167 | 0.9724 | 0.0230 |
| MCF 10A-H2B-mCherry | Alpelisib | 49.15 | 11.9 | Inf | Inf | 0.8148 | 0.8290 | 2.4998 | 0.0068 |
| MCF 10A-H2B-mCherry | Alpelisib | 50.86 | 11.9 | Inf | Inf | 0.8643 | 0.8641 | 2.5000 | 0.0066 |
| MCF 10A-H2B-mCherry | Alpelisib | 52.56 | 11.9 | Inf | Inf | 0.8858 | 0.8764 | 2.5000 | -0.0107 |
| MCF 10A-H2B-mCherry | Alpelisib | 54.25 | 11.9 | Inf | Inf | 0.9331 | 0.9259 | 2.5000 | -0.0161 |
| MCF 10A-H2B-mCherry | Alpelisib | 55.97 | 11.9 | Inf | Inf | 0.9301 | 0.9223 | 2.5000 | -0.0036 |