LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 80.31 | 11.9 | 0.0 | 0.0002 | -1.0000 | -0.8852 | 0.6794 | 1.4491 |
| MCF 10A-H2B-mCherry | Etoposide | 80.31 | 11.9 | Inf | Inf | -0.9514 | -0.9514 | 0.0000 | 1.1514 |
| MCF 10A-H2B-mCherry | Alpelisib | 80.31 | 11.9 | Inf | Inf | -0.9481 | -0.9481 | 0.0000 | 0.4247 |
| MCF 10A-H2B-mCherry | Trametinib | 80.31 | 11.9 | Inf | Inf | 0.1537 | 0.1537 | 0.0000 | 0.4652 |
| MCF 10A-H2B-mCherry | Dasatinib | 80.31 | 11.9 | Inf | Inf | -0.8783 | -0.8783 | 0.0000 | 0.8067 |
| MCF 10A-H2B-mCherry | Vorinostat | 80.31 | 11.9 | Inf | Inf | -0.0761 | -0.0761 | 0.0000 | 0.6257 |
| MCF 10A-H2B-mCherry | Neratinib | 80.31 | 11.9 | Inf | Inf | -1.0000 | -1.0000 | 0.0000 | 0.3828 |
| MCF 10A-H2B-mCherry | Neratinib | 76.90 | 11.9 | Inf | Inf | -1.0000 | -1.0000 | 0.0000 | 0.3500 |
| MCF 10A-H2B-mCherry | Palbociclib | 76.90 | 11.9 | 3.8753 | 4.8812 | -0.9978 | -1.0000 | 4.7782 | 0.1974 |
| MCF 10A-H2B-mCherry | Etoposide | 76.90 | 11.9 | Inf | Inf | -0.8928 | -0.8928 | 0.0000 | 1.0768 |
| MCF 10A-H2B-mCherry | Taxol | 76.90 | 11.9 | 0.0001 | 0.0003 | -0.9743 | -0.6652 | 0.7092 | 1.2470 |
| MCF 10A-H2B-mCherry | Vorinostat | 76.90 | 11.9 | Inf | Inf | -0.0732 | -0.0732 | 0.0000 | 0.4695 |
| MCF 10A-H2B-mCherry | Alpelisib | 76.90 | 11.9 | Inf | Inf | -0.7311 | -0.7311 | 0.0000 | 0.2949 |
| MCF 10A-H2B-mCherry | Trametinib | 76.90 | 11.9 | Inf | Inf | 0.2209 | 0.2209 | 0.0000 | 0.3859 |
| MCF 10A-H2B-mCherry | Dasatinib | 76.90 | 11.9 | Inf | Inf | -0.8342 | -0.8342 | 0.0000 | 0.7051 |
| MCF 10A-H2B-mCherry | Dasatinib | 73.49 | 11.9 | Inf | Inf | -0.7187 | -0.7187 | 0.0000 | 0.6199 |
| MCF 10A-H2B-mCherry | Vorinostat | 73.49 | 11.9 | Inf | Inf | -0.1017 | -0.1017 | 0.0000 | 0.3738 |
| MCF 10A-H2B-mCherry | Etoposide | 73.49 | 11.9 | Inf | Inf | -0.6007 | -0.6007 | 0.0000 | 0.9782 |
| MCF 10A-H2B-mCherry | Trametinib | 73.49 | 11.9 | Inf | Inf | -0.1619 | 0.0708 | 2.5000 | 0.4352 |
| MCF 10A-H2B-mCherry | Neratinib | 73.49 | 11.9 | Inf | Inf | -1.0000 | -1.0000 | 0.0000 | 0.4286 |
| MCF 10A-H2B-mCherry | Palbociclib | 73.49 | 11.9 | 3.8592 | 5.0055 | -0.9830 | -1.0000 | 4.3323 | 0.1600 |
| MCF 10A-H2B-mCherry | Alpelisib | 73.49 | 11.9 | Inf | Inf | -0.1025 | -0.1025 | 0.0000 | 0.1541 |
| MCF 10A-H2B-mCherry | Taxol | 73.49 | 11.9 | Inf | Inf | -0.8372 | -0.6518 | 0.5709 | 1.0513 |
| MCF 10A-H2B-mCherry | Vorinostat | 71.30 | 11.9 | Inf | Inf | 0.0118 | 0.0118 | 0.0000 | 0.1999 |
| MCF 10A-H2B-mCherry | Neratinib | 71.30 | 11.9 | Inf | Inf | -0.7067 | -0.7067 | 0.0000 | 0.3198 |