LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Vorinostat | 28.71 | 11.9 | 0.629 | 1.0433 | -0.2095 | -0.3356 | 1.1665 | 0.4172 |
| MCF 10A-H2B-mCherry | Dasatinib | 28.71 | 11.9 | 0.258 | 0.3013 | 0.0083 | -0.0487 | 0.6118 | 0.4169 |
| MCF 10A-H2B-mCherry | Taxol | 28.71 | 11.9 | 0.0016 | 0.0024 | -0.7752 | -0.6453 | 2.1307 | 0.8888 |
| MCF 10A-H2B-mCherry | Trametinib | 28.71 | 11.9 | 0.0019 | 0.0014 | 0.0832 | 0.1492 | 1.8509 | 0.6520 |
| MCF 10A-H2B-mCherry | Etoposide | 28.71 | 11.9 | 0.282 | 0.2635 | 0.0303 | 0.0409 | 1.1655 | 0.3976 |
| MCF 10A-H2B-mCherry | Palbociclib | 28.71 | 11.9 | 0.1921 | 0.1743 | 0.0502 | 0.1399 | 2.7597 | 0.4197 |
| MCF 10A-H2B-mCherry | Taxol | 27.00 | 11.9 | 0.0017 | 0.0026 | -0.8263 | -0.6759 | 2.0774 | 0.8946 |
| MCF 10A-H2B-mCherry | Palbociclib | 27.00 | 11.9 | 0.1687 | 0.1544 | 0.0778 | 0.1703 | 3.2433 | 0.4239 |
| MCF 10A-H2B-mCherry | Trametinib | 27.00 | 11.9 | 0.0019 | 0.0016 | 0.0473 | 0.1162 | 1.2836 | 0.6659 |
| MCF 10A-H2B-mCherry | Etoposide | 27.00 | 11.9 | 0.3204 | 0.3087 | 0.0279 | 0.0223 | 1.0652 | 0.3875 |
| MCF 10A-H2B-mCherry | Dasatinib | 27.00 | 11.9 | 0.2252 | 0.2485 | 0.0269 | -0.0022 | 0.7064 | 0.4282 |
| MCF 10A-H2B-mCherry | Alpelisib | 27.00 | 11.9 | Inf | Inf | 0.6407 | 0.6557 | 0.5188 | 0.0807 |
| MCF 10A-H2B-mCherry | Vorinostat | 27.00 | 11.9 | 0.5682 | 0.7559 | -0.2144 | -0.2450 | 1.4849 | 0.4363 |
| MCF 10A-H2B-mCherry | Neratinib | 27.00 | 11.9 | 0.06 | 0.0926 | -0.2624 | -0.2032 | 1.0642 | 0.4961 |
| MCF 10A-H2B-mCherry | Palbociclib | 25.30 | 11.9 | 0.1483 | 0.1392 | 0.0934 | 0.1739 | 3.2748 | 0.4447 |
| MCF 10A-H2B-mCherry | Alpelisib | 25.30 | 11.9 | Inf | 2.7919 | 0.5162 | 0.5717 | 4.5032 | 0.1028 |
| MCF 10A-H2B-mCherry | Trametinib | 25.30 | 11.9 | 0.0017 | 0.0014 | 0.1022 | 0.1419 | 1.1785 | 0.6613 |
| MCF 10A-H2B-mCherry | Etoposide | 25.30 | 11.9 | 0.3804 | 0.3361 | 0.0269 | 0.0627 | 1.0177 | 0.3559 |
| MCF 10A-H2B-mCherry | Dasatinib | 25.30 | 11.9 | 0.1978 | 0.2226 | 0.0489 | 0.0284 | 0.7503 | 0.4393 |
| MCF 10A-H2B-mCherry | Neratinib | 25.30 | 11.9 | 0.0433 | 0.0502 | -0.1661 | -0.0752 | 1.0775 | 0.5110 |
| MCF 10A-H2B-mCherry | Vorinostat | 25.30 | 11.9 | 0.5083 | 0.8386 | -0.2192 | -0.3315 | 1.1633 | 0.4556 |
| MCF 10A-H2B-mCherry | Taxol | 25.30 | 11.9 | 0.0017 | 0.0028 | -0.8322 | -0.6866 | 1.8062 | 0.8951 |
| MCF 10A-H2B-mCherry | Taxol | 23.60 | 11.9 | 0.0016 | 0.0029 | -0.7608 | -0.6627 | 1.5068 | 0.8837 |
| MCF 10A-H2B-mCherry | Palbociclib | 23.60 | 11.9 | 0.1293 | 4.9077 | 0.0535 | -0.4107 | 0.6847 | 0.4909 |
| MCF 10A-H2B-mCherry | Etoposide | 23.60 | 11.9 | 0.4333 | 0.3681 | 0.0325 | 0.0929 | 0.9623 | 0.3221 |