LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 38.93 | 11.9 | 0.001 | 0.0013 | -0.6088 | -0.4753 | 2.3261 | 0.8982 |
| MCF 10A-H2B-mCherry | Taxol | 55.97 | 11.9 | 0.0014 | 0.0017 | -0.6141 | -0.5226 | 3.9626 | 0.9101 |
| MCF 10A-H2B-mCherry | Taxol | 16.79 | 11.9 | 0.0027 | 0.0126 | -0.6222 | -0.8419 | 0.7095 | 0.7366 |
| MCF 10A-H2B-mCherry | Taxol | 33.82 | 11.9 | 0.0013 | 0.0018 | -0.6239 | -0.5526 | 2.3121 | 0.8967 |
| MCF 10A-H2B-mCherry | Trametinib | 71.30 | 11.9 | 0.079 | 0.178 | -0.6252 | -0.6343 | 1.6738 | 0.3995 |
| MCF 10A-H2B-mCherry | Neratinib | 54.25 | 11.9 | 0.45 | 1.3349 | -0.6369 | -0.9728 | 1.2215 | 0.2717 |
| MCF 10A-H2B-mCherry | Taxol | 40.63 | 11.9 | 0.0009 | 0.0013 | -0.6378 | -0.4639 | 2.4621 | 0.8999 |
| MCF 10A-H2B-mCherry | Taxol | 42.33 | 11.9 | 0.0009 | 0.0013 | -0.6426 | -0.5128 | 2.3074 | 0.9302 |
| MCF 10A-H2B-mCherry | Taxol | 18.49 | 11.9 | 0.0018 | 0.0057 | -0.6429 | -0.7171 | 0.7731 | 0.7994 |
| MCF 10A-H2B-mCherry | Taxol | 50.86 | 11.9 | 0.0011 | 0.0014 | -0.6471 | -0.4615 | 2.5981 | 0.9039 |
| MCF 10A-H2B-mCherry | Dasatinib | 67.89 | 11.9 | Inf | Inf | -0.6482 | -0.9446 | 0.2134 | 0.3543 |
| MCF 10A-H2B-mCherry | Taxol | 44.03 | 11.9 | 0.0009 | 0.0013 | -0.6620 | -0.5136 | 2.4572 | 0.9282 |
| MCF 10A-H2B-mCherry | Taxol | 35.52 | 11.9 | 0.0011 | 0.0016 | -0.6623 | -0.5487 | 1.8986 | 0.9134 |
| MCF 10A-H2B-mCherry | Neratinib | 62.78 | 11.9 | 0.3552 | 0.4164 | -0.6718 | -0.4322 | 3.7868 | 0.3386 |
| MCF 10A-H2B-mCherry | Taxol | 47.45 | 11.9 | 0.001 | 0.0014 | -0.6791 | -0.5351 | 2.4484 | 0.9236 |
| MCF 10A-H2B-mCherry | Neratinib | 67.89 | 11.9 | 0.459 | 0.8951 | -0.6805 | -0.7165 | 3.0736 | 0.3488 |
| MCF 10A-H2B-mCherry | Taxol | 62.78 | 11.9 | 0.0014 | 0.0017 | -0.6938 | -0.5140 | 4.2755 | 0.9151 |
| MCF 10A-H2B-mCherry | Neratinib | 57.67 | 11.9 | 0.4637 | 1.3072 | -0.6943 | -1.0000 | 1.2533 | 0.2654 |
| MCF 10A-H2B-mCherry | Taxol | 32.11 | 11.9 | 0.0014 | 0.002 | -0.6946 | -0.5659 | 2.4493 | 0.8756 |
| MCF 10A-H2B-mCherry | Neratinib | 55.97 | 11.9 | 0.4248 | 1.1732 | -0.6983 | -1.0000 | 1.2159 | 0.2772 |
| MCF 10A-H2B-mCherry | Neratinib | 71.30 | 11.9 | Inf | Inf | -0.7067 | -0.7067 | 0.0000 | 0.3198 |
| MCF 10A-H2B-mCherry | Taxol | 49.15 | 11.9 | 0.0011 | 0.0014 | -0.7087 | -0.4671 | 2.6462 | 0.8938 |
| MCF 10A-H2B-mCherry | Dasatinib | 69.60 | 11.9 | Inf | Inf | -0.7093 | -0.7093 | 0.0000 | 0.3803 |
| MCF 10A-H2B-mCherry | Neratinib | 64.49 | 11.9 | 0.3607 | 0.4759 | -0.7163 | -0.5720 | 3.3539 | 0.3509 |
| MCF 10A-H2B-mCherry | Neratinib | 61.08 | 11.9 | 0.3193 | 0.4739 | -0.7166 | -0.5803 | 1.8981 | 0.3308 |