LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 15 of 15: Time-dependent dose-response metrics for biological replicate 3. - Dataset (ID:20323)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 62.78 | 11.9 | 0.0014 | 0.0017 | -0.6938 | -0.5140 | 4.2755 | 0.9151 |
| MCF 10A-H2B-mCherry | Taxol | 35.52 | 11.9 | 0.0011 | 0.0016 | -0.6623 | -0.5487 | 1.8986 | 0.9134 |
| MCF 10A-H2B-mCherry | Taxol | 55.97 | 11.9 | 0.0014 | 0.0017 | -0.6141 | -0.5226 | 3.9626 | 0.9101 |
| MCF 10A-H2B-mCherry | Taxol | 59.37 | 11.9 | 0.0014 | 0.0017 | -0.5953 | -0.4995 | 4.0561 | 0.9069 |
| MCF 10A-H2B-mCherry | Taxol | 50.86 | 11.9 | 0.0011 | 0.0014 | -0.6471 | -0.4615 | 2.5981 | 0.9039 |
| MCF 10A-H2B-mCherry | Taxol | 40.63 | 11.9 | 0.0009 | 0.0013 | -0.6378 | -0.4639 | 2.4621 | 0.8999 |
| MCF 10A-H2B-mCherry | Taxol | 37.23 | 11.9 | 0.001 | 0.0014 | -0.5921 | -0.4954 | 2.0788 | 0.8997 |
| MCF 10A-H2B-mCherry | Taxol | 38.93 | 11.9 | 0.001 | 0.0013 | -0.6088 | -0.4753 | 2.3261 | 0.8982 |
| MCF 10A-H2B-mCherry | Alpelisib | 85.43 | 11.9 | Inf | Inf | -0.9874 | -0.9874 | 0.0000 | 0.8979 |
| MCF 10A-H2B-mCherry | Taxol | 33.82 | 11.9 | 0.0013 | 0.0018 | -0.6239 | -0.5526 | 2.3121 | 0.8967 |
| MCF 10A-H2B-mCherry | Taxol | 25.30 | 11.9 | 0.0017 | 0.0028 | -0.8322 | -0.6866 | 1.8062 | 0.8951 |
| MCF 10A-H2B-mCherry | Taxol | 27.00 | 11.9 | 0.0017 | 0.0026 | -0.8263 | -0.6759 | 2.0774 | 0.8946 |
| MCF 10A-H2B-mCherry | Taxol | 49.15 | 11.9 | 0.0011 | 0.0014 | -0.7087 | -0.4671 | 2.6462 | 0.8938 |
| MCF 10A-H2B-mCherry | Taxol | 28.71 | 11.9 | 0.0016 | 0.0024 | -0.7752 | -0.6453 | 2.1307 | 0.8888 |
| MCF 10A-H2B-mCherry | Alpelisib | 85.43 | 12.0 | Inf | Inf | -0.9870 | -0.9870 | 0.0000 | 0.8881 |
| MCF 10A-H2B-mCherry | Taxol | 23.60 | 11.9 | 0.0016 | 0.0029 | -0.7608 | -0.6627 | 1.5068 | 0.8837 |
| MCF 10A-H2B-mCherry | Taxol | 30.41 | 11.9 | 0.0015 | 0.0022 | -0.7435 | -0.6127 | 2.1579 | 0.8791 |
| MCF 10A-H2B-mCherry | Taxol | 32.11 | 11.9 | 0.0014 | 0.002 | -0.6946 | -0.5659 | 2.4493 | 0.8756 |
| MCF 10A-H2B-mCherry | Taxol | 21.90 | 11.9 | 0.0015 | 0.0031 | -0.7607 | -0.6638 | 1.1472 | 0.8704 |
| MCF 10A-H2B-mCherry | Taxol | 64.49 | 11.9 | 0.0016 | 0.0018 | -0.4233 | -0.4418 | 5.0000 | 0.8544 |
| MCF 10A-H2B-mCherry | Taxol | 20.19 | 11.9 | 0.0017 | 0.004 | -0.7188 | -0.6844 | 1.0554 | 0.8484 |
| MCF 10A-H2B-mCherry | Taxol | 54.25 | 11.9 | 0.0012 | 0.0014 | -0.5929 | -0.3570 | 3.0694 | 0.8324 |
| MCF 10A-H2B-mCherry | Dasatinib | 80.31 | 11.9 | Inf | Inf | -0.8783 | -0.8783 | 0.0000 | 0.8067 |
| MCF 10A-H2B-mCherry | Taxol | 18.49 | 11.9 | 0.0018 | 0.0057 | -0.6429 | -0.7171 | 0.7731 | 0.7994 |
| MCF 10A-H2B-mCherry | Trametinib | 89.69 | 11.9 | Inf | Inf | -0.1007 | -0.1007 | 0.0000 | 0.7813 |