LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 14 of 15: Time-dependent dose-response metrics for biological replicate 2. - Dataset (ID:20322)
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| Cell | Small Molecule | Time Point (hr) | Time Interval (hr) | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC |
|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Dasatinib | 46.00 | 11.8 | 1.925 | 11.0714 | -0.0764 | -1.0000 | 0.7940 | 0.2467 |
| MCF 10A-H2B-mCherry | Dasatinib | 40.10 | 11.8 | 1.6021 | 11.394 | -0.0635 | -1.0000 | 0.6554 | 0.2648 |
| MCF 10A-H2B-mCherry | Dasatinib | 26.31 | 11.8 | 0.6274 | 15.1152 | -0.0263 | -1.0000 | 0.3476 | 0.3868 |
| MCF 10A-H2B-mCherry | Palbociclib | 84.44 | 11.8 | 7.8009 | 9.9225 | -0.0850 | -1.0000 | 5.0000 | 0.0239 |
| MCF 10A-H2B-mCherry | Dasatinib | 34.19 | 11.8 | 1.228 | 11.8316 | -0.0560 | -1.0000 | 0.4857 | 0.3070 |
| MCF 10A-H2B-mCherry | Dasatinib | 64.24 | 12.8 | 7.076 | 8.823 | -0.3039 | -1.0000 | 5.0000 | 0.1184 |
| MCF 10A-H2B-mCherry | Dasatinib | 24.34 | 11.8 | 0.5409 | 14.19 | -0.0125 | -1.0000 | 0.3449 | 0.4043 |
| MCF 10A-H2B-mCherry | Dasatinib | 28.28 | 11.8 | 0.7954 | 18.5915 | -0.0078 | -1.0000 | 0.3491 | 0.3618 |
| MCF 10A-H2B-mCherry | Dasatinib | 42.07 | 11.8 | 1.5059 | 10.9559 | -0.0895 | -1.0000 | 0.6771 | 0.2737 |
| MCF 10A-H2B-mCherry | Dasatinib | 44.04 | 11.8 | 1.6363 | 11.3607 | -0.0896 | -1.0000 | 0.7451 | 0.2671 |
| MCF 10A-H2B-mCherry | Dasatinib | 22.37 | 11.8 | 0.4115 | 15.4623 | 0.0244 | -1.0000 | 0.3218 | 0.4271 |
| MCF 10A-H2B-mCherry | Dasatinib | 32.22 | 11.8 | 1.1811 | 12.756 | -0.0495 | -1.0000 | 0.4626 | 0.3081 |
| MCF 10A-H2B-mCherry | Dasatinib | 30.24 | 11.8 | 1.0071 | 14.9742 | -0.0381 | -1.0000 | 0.4085 | 0.3298 |
| MCF 10A-H2B-mCherry | Dasatinib | 38.13 | 11.8 | 1.2309 | 14.7989 | -0.0305 | -1.0000 | 0.4484 | 0.3159 |
| MCF 10A-H2B-mCherry | Dasatinib | 36.16 | 11.8 | 1.1086 | 14.38 | -0.0457 | -1.0000 | 0.4301 | 0.3274 |
| MCF 10A-H2B-mCherry | Neratinib | 74.59 | 11.8 | Inf | Inf | -0.7181 | -0.9989 | 0.6470 | 0.4952 |
| MCF 10A-H2B-mCherry | Neratinib | 72.62 | 11.8 | Inf | Inf | -0.6829 | -0.9987 | 0.4021 | 0.4642 |
| MCF 10A-H2B-mCherry | Neratinib | 78.53 | 11.8 | Inf | Inf | -0.7553 | -0.9963 | 1.0525 | 0.4438 |
| MCF 10A-H2B-mCherry | Neratinib | 76.56 | 11.8 | Inf | Inf | -0.6488 | -0.9900 | 0.4587 | 0.4979 |
| MCF 10A-H2B-mCherry | Dasatinib | 16.47 | 11.8 | 0.2976 | 18.1565 | 0.0567 | -0.9754 | 0.3022 | 0.4478 |
| MCF 10A-H2B-mCherry | Dasatinib | 84.44 | 11.8 | Inf | Inf | -0.9625 | -0.9625 | 0.0000 | 0.4367 |
| MCF 10A-H2B-mCherry | Neratinib | 70.65 | 11.8 | 0.409 | 0.8755 | -0.7838 | -0.9606 | 2.1901 | 0.4163 |
| MCF 10A-H2B-mCherry | Taxol | 22.37 | 11.8 | 0.0022 | 0.0052 | -0.9405 | -0.9510 | 1.3001 | 0.9473 |
| MCF 10A-H2B-mCherry | Taxol | 20.40 | 11.8 | 0.0027 | 0.0057 | -0.9423 | -0.9486 | 1.4238 | 0.9269 |
| MCF 10A-H2B-mCherry | Dasatinib | 82.47 | 11.8 | Inf | Inf | -0.9461 | -0.9461 | 0.0000 | 0.4375 |