LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 8 of 15: End-point dose-response metrics for biological replicate 2. - Dataset (ID:20316)

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Cell Small Molecule Time Point (hr) GR50 GEC50 GRmax GRinf GR Hill Coefficient GR_AOC
MCF 10A-H2B-mCherry Alpelisib 12
Inf
Inf
0.5346 0.5346 0.0000 0.4462
MCF 10A-H2B-mCherry Alpelisib 24
Inf
Inf
0.6050 0.6050 0.0000 0.3309
MCF 10A-H2B-mCherry Alpelisib 36
Inf
Inf
0.7055 0.7055 0.0000 0.2829
MCF 10A-H2B-mCherry Alpelisib 48
Inf
Inf
0.7368 0.7368 0.0000 0.2612
MCF 10A-H2B-mCherry Alpelisib 72
Inf
Inf
0.8047 0.8047 0.0000 0.2441
MCF 10A-H2B-mCherry Alpelisib 84
Inf
Inf
0.7374 0.7374 0.0000 0.3018
MCF 10A-H2B-mCherry Dasatinib 12
Inf
Inf
0.4761 0.4761 0.0000 0.4903
MCF 10A-H2B-mCherry Dasatinib 24
Inf
Inf
0.3885 0.3885 0.0000 0.4429
MCF 10A-H2B-mCherry Dasatinib 36
Inf
Inf
0.3554 0.3554 0.0000 0.4191
MCF 10A-H2B-mCherry Dasatinib 48
Inf
Inf
0.3357 0.3357 0.0000 0.3927
MCF 10A-H2B-mCherry Dasatinib 72
Inf
Inf
0.2033 0.2033 0.0000 0.3884
MCF 10A-H2B-mCherry Dasatinib 84
Inf
Inf
0.1459 0.1459 0.0000 0.4301
MCF 10A-H2B-mCherry Etoposide 12
Inf
Inf
0.3263 0.3263 0.0000 0.4338
MCF 10A-H2B-mCherry Etoposide 24
Inf
Inf
0.2285 0.2285 0.0000 0.3229
MCF 10A-H2B-mCherry Etoposide 36
1.7174
246.1221
0.1871 -1.0000 0.2213 0.3418
MCF 10A-H2B-mCherry Etoposide 48
1.0407
79.7605
0.1715 -1.0000 0.2532 0.3575
MCF 10A-H2B-mCherry Etoposide 72
0.4072
92.5315
0.1613 -1.0000 0.2025 0.4334
MCF 10A-H2B-mCherry Etoposide 84
0.1739
59.2726
0.1678 -1.0000 0.1884 0.4947
MCF 10A-H2B-mCherry Neratinib 12
Inf
Inf
0.4696 0.4696 0.0000 0.4345
MCF 10A-H2B-mCherry Neratinib 24
0.3492
0.0073
0.4236 0.3755 0.3591 0.3870
MCF 10A-H2B-mCherry Neratinib 36
0.1336
0.0994
0.2934 0.0455 0.3225 0.4123
MCF 10A-H2B-mCherry Neratinib 48
0.2009
11.344
0.1627 -1.0000 0.2724 0.3954
MCF 10A-H2B-mCherry Neratinib 72
0.2915
6.6939
0.0859 -1.0000 0.3505 0.3727
MCF 10A-H2B-mCherry Neratinib 84
0.2528
9.4484
0.0272 -1.0000 0.3034 0.3990
MCF 10A-H2B-mCherry Palbociclib 12
Inf
Inf
0.4654 0.4654 0.0000 0.4378
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