LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 6 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 3. - Dataset (ID:20314)
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Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
---|---|---|---|---|---|---|---|---|
MCF 10A-H2B-mCherry | Vorinostat | 10 | 48.30 | 56.33 | 138 | 4875 | 0.0288 | -0.0821 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 65.30 | 56.33 | 129 | 7570 | 0.0175 | -0.0818 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 73.90 | 56.33 | 130 | 8150 | 0.0165 | -0.0817 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 46.60 | 56.33 | 141 | 4538 | 0.0317 | -0.0815 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 70.50 | 56.33 | 127 | 7990 | 0.0164 | -0.0813 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 55.10 | 56.33 | 126 | 6087 | 0.0211 | -0.0813 |
MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 68.70 | 56.33 | 131 | 7933 | 0.0166 | -0.0812 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 60.20 | 56.33 | 130 | 6852 | 0.0194 | -0.0810 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 51.70 | 56.33 | 132 | 5553 | 0.0241 | -0.0802 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 67.00 | 56.33 | 128 | 7731 | 0.0171 | -0.0797 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 79.00 | 56.33 | 133 | 8048 | 0.0170 | -0.0789 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 80.70 | 56.33 | 132 | 7920 | 0.0171 | -0.0788 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 50.00 | 56.33 | 136 | 5234 | 0.0265 | -0.0787 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 61.90 | 56.33 | 129 | 7075 | 0.0187 | -0.0785 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 63.60 | 56.33 | 128 | 7339 | 0.0178 | -0.0785 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 77.30 | 56.33 | 130 | 8135 | 0.0165 | -0.0779 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 43.20 | 56.33 | 141 | 3942 | 0.0366 | -0.0772 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 68.70 | 56.33 | 132 | 7933 | 0.0171 | -0.0769 |
MCF 10A-H2B-mCherry | Taxol | 0.01 | 36.40 | 56.33 | 150 | 2958 | 0.0540 | -0.0763 |
MCF 10A-H2B-mCherry | Dasatinib | 10 | 87.50 | 56.33 | 197 | 7334 | 0.0274 | -0.0761 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 75.60 | 56.33 | 130 | 7992 | 0.0167 | -0.0761 |
MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 60.20 | 56.33 | 211 | 6852 | 0.0287 | -0.0756 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 44.90 | 56.33 | 144 | 4212 | 0.0347 | -0.0750 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 39.80 | 56.33 | 152 | 3393 | 0.0455 | -0.0711 |
MCF 10A-H2B-mCherry | Vorinostat | 10 | 41.50 | 56.33 | 150 | 3667 | 0.0417 | -0.0702 |