LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 6 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 3. - Dataset (ID:20314)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 29.60 | 56.33 | 741 | 2050 | 0.3682 | 0.5629 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 31.30 | 56.33 | 778 | 2241 | 0.3517 | 0.5700 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 33.00 | 56.33 | 798 | 2479 | 0.3276 | 0.5650 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 34.70 | 56.33 | 817 | 2720 | 0.3050 | 0.5574 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 36.40 | 56.33 | 897 | 2958 | 0.3079 | 0.5699 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 38.10 | 56.33 | 934 | 3168 | 0.2984 | 0.5696 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 39.80 | 56.33 | 947 | 3393 | 0.2816 | 0.5655 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 41.50 | 56.33 | 1036 | 3667 | 0.2856 | 0.5741 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 43.20 | 56.33 | 1051 | 3942 | 0.2691 | 0.5700 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 44.90 | 56.33 | 1092 | 4212 | 0.2608 | 0.5719 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 46.60 | 56.33 | 1126 | 4538 | 0.2511 | 0.5672 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 48.30 | 56.33 | 1196 | 4875 | 0.2478 | 0.5696 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 50.00 | 56.33 | 1233 | 5234 | 0.2372 | 0.5663 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 51.70 | 56.33 | 1281 | 5553 | 0.2330 | 0.5680 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 53.40 | 56.33 | 1315 | 5809 | 0.2286 | 0.5696 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 55.10 | 56.33 | 1373 | 6087 | 0.2277 | 0.5710 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 56.80 | 56.33 | 1405 | 6354 | 0.2240 | 0.5704 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 58.50 | 56.33 | 1469 | 6599 | 0.2257 | 0.5754 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 60.20 | 56.33 | 1519 | 6852 | 0.2258 | 0.5806 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 61.90 | 56.33 | 1535 | 7075 | 0.2208 | 0.5741 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 63.60 | 56.33 | 1581 | 7339 | 0.2196 | 0.5768 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 65.30 | 56.33 | 1639 | 7570 | 0.2208 | 0.5827 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 67.00 | 56.33 | 1668 | 7731 | 0.2210 | 0.5820 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 68.70 | 56.33 | 1716 | 7933 | 0.2219 | 0.5864 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 70.50 | 56.33 | 1751 | 7990 | 0.2251 | 0.5894 |