LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 6 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 3. - Dataset (ID:20314)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 70.50 | 56.33 | 4324 | 7990 | 0.5755 | 0.7649 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 72.20 | 56.33 | 4482 | 8053 | 0.5929 | 0.7726 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 73.90 | 56.33 | 4622 | 8150 | 0.6052 | 0.7777 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 75.60 | 56.33 | 4720 | 7992 | 0.6216 | 0.7816 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 77.30 | 56.33 | 4860 | 8135 | 0.6336 | 0.7858 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 79.00 | 56.33 | 4977 | 8048 | 0.6516 | 0.7922 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 80.70 | 56.33 | 5087 | 7920 | 0.6752 | 0.7967 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 82.40 | 56.33 | 5249 | 7810 | 0.7008 | 0.8064 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 84.10 | 56.33 | 5345 | 7655 | 0.7191 | 0.8120 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 85.80 | 56.33 | 5511 | 7583 | 0.7469 | 0.8233 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 87.50 | 56.33 | 5613 | 7334 | 0.7780 | 0.8270 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 89.20 | 56.33 | 5751 | 7229 | 0.8053 | 0.8325 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 90.90 | 56.33 | 5854 | 7174 | 0.8253 | 0.8367 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 92.60 | 56.33 | 6036 | 7065 | 0.8619 | 0.8465 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 94.30 | 56.33 | 6151 | 6924 | 0.8913 | 0.8428 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 95.70 | 27.76 | 8102 | 6712 | 1.2070 | 1.0347 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 2.30 | 56.33 | 335 | 255 | 1.3342 | 0.6299 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 4.00 | 56.33 | 377 | 303 | 1.2491 | 0.5675 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 5.70 | 56.33 | 414 | 342 | 1.2116 | 0.5382 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 7.40 | 56.33 | 461 | 385 | 1.2008 | 0.5350 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 9.10 | 56.33 | 499 | 424 | 1.1805 | 0.5775 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 10.80 | 56.33 | 547 | 465 | 1.1788 | 0.6243 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 12.50 | 56.33 | 604 | 510 | 1.1882 | 0.7502 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 14.20 | 56.33 | 826 | 634 | 1.3092 | 0.9648 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 15.90 | 56.33 | 967 | 726 | 1.3358 | 0.9953 |