LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 6 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 3. - Dataset (ID:20314)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 68.70 | 56.33 | 6 | 7933 | 0.0008 | -0.3241 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 70.50 | 56.33 | 7 | 7990 | 0.0010 | -0.2993 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 72.20 | 56.33 | 7 | 8053 | 0.0009 | -0.3180 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 73.90 | 56.33 | 7 | 8150 | 0.0009 | -0.3089 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 75.60 | 56.33 | 7 | 7992 | 0.0009 | -0.3315 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 77.30 | 56.33 | 8 | 8135 | 0.0010 | -0.3165 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 79.00 | 56.33 | 5 | 8048 | 0.0007 | -0.3411 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 80.70 | 56.33 | 5 | 7920 | 0.0006 | -0.3332 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 82.40 | 56.33 | 5 | 7810 | 0.0007 | -0.3278 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 84.10 | 56.33 | 4 | 7655 | 0.0006 | -0.3444 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 85.80 | 56.33 | 3 | 7583 | 0.0005 | -0.3550 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 87.50 | 56.33 | 4 | 7334 | 0.0006 | -0.3471 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 89.20 | 56.33 | 4 | 7229 | 0.0006 | -0.3438 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 90.90 | 56.33 | 3 | 7174 | 0.0005 | -0.3624 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 92.60 | 56.33 | 3 | 7065 | 0.0005 | -0.3636 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 94.30 | 56.33 | 3 | 6924 | 0.0005 | -0.3640 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 95.70 | 27.76 | 3 | 6712 | 0.0004 | -0.2902 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 2.30 | 56.33 | 286 | 255 | 1.1446 | 0.5270 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 4.00 | 56.33 | 322 | 303 | 1.0727 | 0.4809 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 5.70 | 56.33 | 368 | 342 | 1.0819 | 0.4700 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 7.40 | 56.33 | 416 | 385 | 1.0879 | 0.4694 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 9.10 | 56.33 | 457 | 424 | 1.0847 | 0.4711 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 10.80 | 56.33 | 489 | 465 | 1.0572 | 0.4979 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 12.50 | 56.33 | 527 | 510 | 1.0366 | 0.5382 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 14.20 | 56.33 | 598 | 634 | 0.9463 | 0.6197 |