LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 6 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 3. - Dataset (ID:20314)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 84.10 | 56.33 | 413 | 7655 | 0.0527 | 0.1665 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 85.80 | 56.33 | 399 | 7583 | 0.0515 | 0.1340 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 87.50 | 56.33 | 394 | 7334 | 0.0529 | 0.1086 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 89.20 | 56.33 | 397 | 7229 | 0.0542 | 0.1140 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 90.90 | 56.33 | 395 | 7174 | 0.0544 | 0.1018 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 92.60 | 56.33 | 393 | 7065 | 0.0551 | 0.1011 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 94.30 | 56.33 | 386 | 6924 | 0.0556 | 0.0860 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 95.70 | 27.76 | 204 | 6712 | 0.0305 | -0.0826 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 2.30 | 56.33 | 312 | 255 | 1.2208 | 0.6070 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 4.00 | 56.33 | 357 | 303 | 1.1781 | 0.5656 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 5.70 | 56.33 | 394 | 342 | 1.1486 | 0.5249 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 7.40 | 56.33 | 441 | 385 | 1.1413 | 0.5073 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 9.10 | 56.33 | 485 | 424 | 1.1419 | 0.5213 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 10.80 | 56.33 | 518 | 465 | 1.1105 | 0.4932 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 12.50 | 56.33 | 545 | 510 | 1.0667 | 0.5295 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 14.20 | 56.33 | 585 | 634 | 0.9208 | 0.4918 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 15.90 | 56.33 | 617 | 726 | 0.8473 | 0.4832 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 17.60 | 56.33 | 675 | 868 | 0.7753 | 0.4697 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 19.30 | 56.33 | 748 | 1090 | 0.6874 | 0.4746 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 21.00 | 56.33 | 832 | 1286 | 0.6461 | 0.5158 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 22.80 | 56.33 | 923 | 1460 | 0.6294 | 0.5163 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 24.50 | 56.33 | 1009 | 1615 | 0.6218 | 0.5490 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 26.20 | 56.33 | 1084 | 1764 | 0.6126 | 0.5701 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 27.90 | 56.33 | 1205 | 1907 | 0.6280 | 0.6179 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 29.60 | 56.33 | 1312 | 2050 | 0.6362 | 0.6224 |