LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 6 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 3. - Dataset (ID:20314)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Neratinib | 0.31623 | 95.70 | 27.76 | 956 | 6712 | 0.1425 | 0.5016 |
| MCF 10A-H2B-mCherry | Neratinib | 0.56234 | 95.70 | 27.76 | 739 | 6712 | 0.1101 | 0.3237 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 95.70 | 27.76 | 2 | 6712 | 0.0004 | -0.2970 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 95.70 | 27.76 | 5847 | 6712 | 0.8712 | 0.7696 |
| MCF 10A-H2B-mCherry | 0 | 95.70 | 27.76 | 6674 | 6712 | 0.9942 | 0.7806 | |
| MCF 10A-H2B-mCherry | Palbociclib | 0.056667 | 95.70 | 27.76 | 4061 | 6712 | 0.6050 | 0.8083 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.17783 | 95.70 | 27.76 | 4615 | 6712 | 0.6876 | 0.8431 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.31623 | 95.70 | 27.76 | 1591 | 6712 | 0.2371 | 0.5571 |
| MCF 10A-H2B-mCherry | Palbociclib | 1.7783 | 95.70 | 27.76 | 1480 | 6712 | 0.2206 | 0.6080 |
| MCF 10A-H2B-mCherry | Palbociclib | 3.1623 | 95.70 | 27.76 | 1425 | 6712 | 0.2124 | 0.6326 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 95.70 | 27.76 | 204 | 6712 | 0.0305 | -0.0826 |
| MCF 10A-H2B-mCherry | Taxol | 0.000043333 | 95.70 | 27.76 | 7054 | 6712 | 1.0509 | 0.8033 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.0033333 | 95.70 | 27.76 | 5343 | 6712 | 0.7960 | 0.6904 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.01 | 95.70 | 27.76 | 8717 | 6712 | 1.2987 | 0.9937 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.1 | 95.70 | 27.76 | 6364 | 6712 | 0.9481 | 0.8755 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 95.70 | 27.76 | 7093 | 6712 | 1.0567 | 0.9927 |
| MCF 10A-H2B-mCherry | Alpelisib | 1.7783 | 95.70 | 27.76 | 6242 | 6712 | 0.9300 | 0.9316 |
| MCF 10A-H2B-mCherry | Alpelisib | 3.1623 | 95.70 | 27.76 | 5679 | 6712 | 0.8460 | 0.7377 |
| MCF 10A-H2B-mCherry | Alpelisib | 10 | 95.70 | 27.76 | 2136 | 6712 | 0.3182 | 0.4870 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0010833 | 95.70 | 27.76 | 6108 | 6712 | 0.9100 | 0.8657 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.031667 | 95.70 | 27.76 | 3379 | 6712 | 0.5034 | 0.5530 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.056667 | 95.70 | 27.76 | 3718 | 6712 | 0.5539 | 0.6820 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.17783 | 95.70 | 27.76 | 2855 | 6712 | 0.4253 | 0.5826 |
| MCF 10A-H2B-mCherry | Taxol | 0.0018 | 95.70 | 27.76 | 1364 | 6712 | 0.2032 | 0.2590 |
| MCF 10A-H2B-mCherry | Taxol | 0.001 | 95.70 | 27.76 | 3343 | 6712 | 0.4980 | 0.3525 |