LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 6 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 3. - Dataset (ID:20314)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Etoposide | 1.7783 | 95.70 | 27.76 | 539 | 6712 | 0.0803 | 0.2101 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 95.70 | 27.76 | 8720 | 6712 | 1.2991 | 0.9699 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0013333 | 95.70 | 27.76 | 7375 | 6712 | 1.0988 | 0.8562 |
| MCF 10A-H2B-mCherry | Neratinib | 0.0053333 | 95.70 | 27.76 | 6537 | 6712 | 0.9738 | 0.8196 |
| MCF 10A-H2B-mCherry | Neratinib | 0.01 | 95.70 | 27.76 | 4440 | 6712 | 0.6616 | 0.5850 |
| MCF 10A-H2B-mCherry | 0 | 95.70 | 27.76 | 6674 | 6712 | 0.9942 | 0.7806 | |
| MCF 10A-H2B-mCherry | Alpelisib | 0.0033333 | 95.70 | 27.76 | 5343 | 6712 | 0.7960 | 0.6904 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.031667 | 95.70 | 27.76 | 6148 | 6712 | 0.9159 | 0.8581 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.1 | 95.70 | 27.76 | 6364 | 6712 | 0.9481 | 0.8755 |
| MCF 10A-H2B-mCherry | Alpelisib | 1 | 95.70 | 27.76 | 6428 | 6712 | 0.9576 | 0.9174 |
| MCF 10A-H2B-mCherry | Alpelisib | 1.7783 | 95.70 | 27.76 | 6242 | 6712 | 0.9300 | 0.9316 |
| MCF 10A-H2B-mCherry | Alpelisib | 5.6234 | 95.70 | 27.76 | 4675 | 6712 | 0.6965 | 0.6828 |
| MCF 10A-H2B-mCherry | Alpelisib | 10 | 95.70 | 27.76 | 2136 | 6712 | 0.3182 | 0.4870 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.018333 | 95.70 | 27.76 | 3408 | 6712 | 0.5078 | 0.5699 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.031667 | 95.70 | 27.76 | 3379 | 6712 | 0.5034 | 0.5530 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.1 | 95.70 | 27.76 | 2000 | 6712 | 0.2980 | 0.5394 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.17783 | 95.70 | 27.76 | 2855 | 6712 | 0.4253 | 0.5826 |
| MCF 10A-H2B-mCherry | Dasatinib | 1 | 95.70 | 27.76 | 1133 | 6712 | 0.1688 | 0.3135 |
| MCF 10A-H2B-mCherry | Dasatinib | 1.7783 | 95.70 | 27.76 | 2236 | 6712 | 0.3331 | 0.6154 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 95.70 | 27.76 | 232 | 6712 | 0.0347 | 0.0543 |
| MCF 10A-H2B-mCherry | Etoposide | 0.0010833 | 95.70 | 27.76 | 8661 | 6712 | 1.2903 | 0.9277 |
| MCF 10A-H2B-mCherry | Etoposide | 0.056667 | 95.70 | 27.76 | 6706 | 6712 | 0.9991 | 0.8506 |
| MCF 10A-H2B-mCherry | Etoposide | 0.1 | 95.70 | 27.76 | 7113 | 6712 | 1.0597 | 0.9132 |
| MCF 10A-H2B-mCherry | Neratinib | 0.17783 | 95.70 | 27.76 | 2657 | 6712 | 0.3959 | 0.7259 |
| MCF 10A-H2B-mCherry | Neratinib | 0.1 | 95.70 | 27.76 | 4219 | 6712 | 0.6286 | 0.8610 |