LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 6 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 3. - Dataset (ID:20314)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 72.20 | 56.33 | 8364 | 8053 | 1.0510 | 0.9713 |
| MCF 10A-H2B-mCherry | Etoposide | 0.018333 | 94.30 | 56.33 | 8367 | 6924 | 1.2065 | 1.0101 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 85.80 | 56.33 | 8382 | 7583 | 1.1108 | 0.9525 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 85.80 | 56.33 | 8407 | 7583 | 1.1190 | 0.9794 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 90.90 | 56.33 | 8440 | 7174 | 1.1784 | 0.9903 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 87.50 | 56.33 | 8446 | 7334 | 1.1568 | 0.9877 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 89.20 | 56.33 | 8458 | 7229 | 1.1729 | 0.9876 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 73.90 | 56.33 | 8476 | 8150 | 1.0528 | 0.9727 |
| MCF 10A-H2B-mCherry | Etoposide | 0.018333 | 92.60 | 56.33 | 8485 | 7065 | 1.1974 | 1.0201 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 85.80 | 56.33 | 8486 | 7583 | 1.1272 | 0.9851 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 75.60 | 56.33 | 8507 | 7992 | 1.0734 | 0.9750 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 87.50 | 56.33 | 8514 | 7334 | 1.1631 | 0.9645 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 84.10 | 56.33 | 8516 | 7655 | 1.1193 | 0.9833 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 77.30 | 56.33 | 8526 | 8135 | 1.0617 | 0.9694 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 79.00 | 56.33 | 8563 | 8048 | 1.0760 | 0.9732 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 80.70 | 56.33 | 8579 | 7920 | 1.0963 | 0.9800 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 82.40 | 56.33 | 8584 | 7810 | 1.1100 | 0.9809 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0033333 | 95.70 | 27.76 | 8602 | 6712 | 1.2815 | 0.9824 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 89.20 | 56.33 | 8626 | 7229 | 1.1945 | 0.9706 |
| MCF 10A-H2B-mCherry | Etoposide | 0.018333 | 65.30 | 56.33 | 8659 | 7570 | 1.1553 | 1.0364 |
| MCF 10A-H2B-mCherry | Etoposide | 0.0010833 | 95.70 | 27.76 | 8661 | 6712 | 1.2903 | 0.9277 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 95.70 | 27.76 | 8684 | 6712 | 1.2938 | 1.0076 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.01 | 90.90 | 56.33 | 8716 | 7174 | 1.2162 | 0.9704 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.01 | 95.70 | 27.76 | 8717 | 6712 | 1.2987 | 0.9937 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 95.70 | 27.76 | 8720 | 6712 | 1.2991 | 0.9699 |