LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 6 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 3. - Dataset (ID:20314)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 29.60 | 56.33 | 139 | 2050 | 0.0691 | -0.0347 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 43.20 | 56.33 | 141 | 3942 | 0.0366 | -0.0772 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 46.60 | 56.33 | 141 | 4538 | 0.0317 | -0.0815 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 85.80 | 56.33 | 143 | 7583 | 0.0191 | -0.0477 |
| MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 94.30 | 56.33 | 143 | 6924 | 0.0207 | -0.0492 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 44.90 | 56.33 | 144 | 4212 | 0.0347 | -0.0750 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 87.50 | 56.33 | 144 | 7334 | 0.0189 | -0.1809 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 89.20 | 56.33 | 145 | 7229 | 0.0203 | -0.0396 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 87.50 | 56.33 | 145 | 7334 | 0.0200 | -0.0431 |
| MCF 10A-H2B-mCherry | Taxol | 0.01 | 38.10 | 56.33 | 145 | 3168 | 0.0484 | -0.0928 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.31623 | 2.30 | 56.33 | 146 | 255 | 0.5345 | 0.0586 |
| MCF 10A-H2B-mCherry | Taxol | 0.1 | 17.60 | 56.33 | 148 | 868 | 0.1721 | 0.0158 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 27.90 | 56.33 | 149 | 1907 | 0.0803 | -0.0269 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 41.50 | 56.33 | 150 | 3667 | 0.0417 | -0.0702 |
| MCF 10A-H2B-mCherry | Taxol | 0.01 | 36.40 | 56.33 | 150 | 2958 | 0.0540 | -0.0763 |
| MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 92.60 | 56.33 | 150 | 7065 | 0.0212 | -0.0399 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 90.90 | 56.33 | 150 | 7174 | 0.0211 | -0.0385 |
| MCF 10A-H2B-mCherry | Taxol | 0.017783 | 22.80 | 56.33 | 151 | 1460 | 0.1060 | -0.0437 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 17.60 | 56.33 | 152 | 868 | 0.1749 | -0.0043 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 39.80 | 56.33 | 152 | 3393 | 0.0455 | -0.0711 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 79.00 | 56.33 | 154 | 8048 | 0.0171 | -0.1527 |
| MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 90.90 | 56.33 | 154 | 7174 | 0.0215 | -0.0433 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 90.90 | 56.33 | 155 | 7174 | 0.0209 | -0.1865 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 92.60 | 56.33 | 155 | 7065 | 0.0221 | -0.0347 |
| MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 89.20 | 56.33 | 155 | 7229 | 0.0214 | -0.0394 |