LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 6 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 3. - Dataset (ID:20314)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Alpelisib | 3.1623 | 95.70 | 27.76 | 5679 | 6712 | 0.8460 | 0.7377 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 95.70 | 27.76 | 2 | 6712 | 0.0004 | -0.2970 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.56234 | 95.70 | 27.76 | 2676 | 6712 | 0.3987 | 0.6801 |
| MCF 10A-H2B-mCherry | Etoposide | 0.0033333 | 95.70 | 27.76 | 3453 | 6712 | 0.5145 | 0.5190 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0010833 | 95.70 | 27.76 | 6108 | 6712 | 0.9100 | 0.8657 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 95.70 | 27.76 | 450 | 6712 | 0.0671 | 0.2396 |
| MCF 10A-H2B-mCherry | Etoposide | 0.018333 | 95.70 | 27.76 | 7029 | 6712 | 1.0472 | 0.9167 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.031667 | 95.70 | 27.76 | 4042 | 6712 | 0.6022 | 0.5174 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 95.70 | 27.76 | 970 | 6712 | 0.1445 | 0.5557 |
| MCF 10A-H2B-mCherry | Etoposide | 0.17783 | 95.70 | 27.76 | 3005 | 6712 | 0.4477 | 0.5545 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.01 | 95.70 | 27.76 | 8717 | 6712 | 1.2987 | 0.9937 |
| MCF 10A-H2B-mCherry | Etoposide | 0.01 | 95.70 | 27.76 | 3315 | 6712 | 0.4940 | 0.4878 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 95.70 | 27.76 | 5847 | 6712 | 0.8712 | 0.7696 |
| MCF 10A-H2B-mCherry | Taxol | 0.0018 | 95.70 | 27.76 | 1364 | 6712 | 0.2032 | 0.2590 |
| MCF 10A-H2B-mCherry | Palbociclib | 5.6234 | 95.70 | 27.76 | 868 | 6712 | 0.1294 | 0.5102 |
| MCF 10A-H2B-mCherry | Vorinostat | 1 | 95.70 | 27.76 | 2493 | 6712 | 0.3715 | 0.5033 |
| MCF 10A-H2B-mCherry | Neratinib | 0.01 | 95.70 | 27.76 | 4440 | 6712 | 0.6616 | 0.5850 |
| MCF 10A-H2B-mCherry | Etoposide | 1.7783 | 95.70 | 27.76 | 539 | 6712 | 0.0803 | 0.2101 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 95.70 | 27.76 | 1506 | 6712 | 0.2245 | 0.6016 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.17783 | 95.70 | 27.76 | 4615 | 6712 | 0.6876 | 0.8431 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00066667 | 95.70 | 27.76 | 5381 | 6712 | 0.8017 | 0.8674 |
| MCF 10A-H2B-mCherry | Palbociclib | 1.7783 | 95.70 | 27.76 | 1480 | 6712 | 0.2206 | 0.6080 |
| MCF 10A-H2B-mCherry | Neratinib | 0.056234 | 95.70 | 27.76 | 5221 | 6712 | 0.7779 | 0.8202 |
| MCF 10A-H2B-mCherry | Alpelisib | 10 | 95.70 | 27.76 | 2136 | 6712 | 0.3182 | 0.4870 |
| MCF 10A-H2B-mCherry | 0 | 95.70 | 27.76 | 6674 | 6712 | 0.9942 | 0.7806 |