LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 6 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 3. - Dataset (ID:20314)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Palbociclib | 0.17783 | 92.60 | 56.33 | 4835 | 7065 | 0.6834 | 0.8224 |
| MCF 10A-H2B-mCherry | Dasatinib | 3.1623 | 92.60 | 56.33 | 895 | 7065 | 0.1266 | 0.3617 |
| MCF 10A-H2B-mCherry | Alpelisib | 10 | 92.60 | 56.33 | 3023 | 7065 | 0.4253 | 0.6096 |
| MCF 10A-H2B-mCherry | Etoposide | 3.1623 | 92.60 | 56.33 | 362 | 7065 | 0.0512 | 0.1618 |
| MCF 10A-H2B-mCherry | Taxol | 0.0002 | 92.60 | 56.33 | 6082 | 7065 | 0.8628 | 0.8190 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 92.60 | 56.33 | 7867 | 7065 | 1.1185 | 0.9190 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.031667 | 92.60 | 56.33 | 7380 | 7065 | 1.0355 | 0.8292 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.31623 | 92.60 | 56.33 | 3640 | 7065 | 0.5157 | 0.6456 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.31623 | 92.60 | 56.33 | 8099 | 7065 | 1.1468 | 0.9775 |
| MCF 10A-H2B-mCherry | Taxol | 0.017783 | 92.60 | 56.33 | 5 | 7065 | 0.0007 | -0.3230 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.56234 | 92.60 | 56.33 | 3647 | 7065 | 0.5124 | 0.7674 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.31623 | 92.60 | 56.33 | 6069 | 7065 | 0.8546 | 0.8035 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 92.60 | 56.33 | 40 | 7065 | 0.0058 | -0.1569 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00033333 | 92.60 | 56.33 | 6535 | 7065 | 0.9281 | 0.8136 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.1 | 92.60 | 56.33 | 2867 | 7065 | 0.4044 | 0.5989 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 92.60 | 56.33 | 5230 | 7065 | 0.7347 | 0.7078 |
| MCF 10A-H2B-mCherry | Alpelisib | 0.0033333 | 92.60 | 56.33 | 6892 | 7065 | 0.9714 | 0.7923 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 92.60 | 56.33 | 3 | 7065 | 0.0005 | -0.3636 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.01 | 92.60 | 56.33 | 7361 | 7065 | 1.0438 | 0.9000 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 92.60 | 56.33 | 6036 | 7065 | 0.8619 | 0.8465 |
| MCF 10A-H2B-mCherry | Palbociclib | 1 | 92.60 | 56.33 | 1837 | 7065 | 0.2589 | 0.5544 |
| MCF 10A-H2B-mCherry | Alpelisib | 1 | 92.60 | 56.33 | 6122 | 7065 | 0.8689 | 0.8383 |
| MCF 10A-H2B-mCherry | Taxol | 0.00033333 | 92.60 | 56.33 | 6275 | 7065 | 0.8841 | 0.7606 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 92.60 | 56.33 | 6031 | 7065 | 0.8527 | 0.7807 |
| MCF 10A-H2B-mCherry | Dasatinib | 1.7783 | 92.60 | 56.33 | 2394 | 7065 | 0.3383 | 0.6158 |