LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 6 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 3. - Dataset (ID:20314)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 0.1 | 29.60 | 56.33 | 47 | 2050 | 0.0238 | -0.2322 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 94.30 | 56.33 | 164 | 6924 | 0.0239 | -0.1206 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 94.30 | 56.33 | 167 | 6924 | 0.0240 | -0.1951 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 51.70 | 56.33 | 132 | 5553 | 0.0241 | -0.0802 |
| MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 84.10 | 56.33 | 186 | 7655 | 0.0243 | -0.0234 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 65.30 | 56.33 | 189 | 7570 | 0.0247 | -0.0515 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 92.60 | 56.33 | 172 | 7065 | 0.0248 | -0.1123 |
| MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 82.40 | 56.33 | 195 | 7810 | 0.0251 | -0.0208 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 90.90 | 56.33 | 179 | 7174 | 0.0254 | -0.1152 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 63.60 | 56.33 | 203 | 7339 | 0.0255 | -0.0856 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 61.90 | 56.33 | 200 | 7075 | 0.0261 | -0.0829 |
| MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 79.00 | 56.33 | 210 | 8048 | 0.0263 | -0.0190 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 60.20 | 56.33 | 179 | 6852 | 0.0265 | -0.0545 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 50.00 | 56.33 | 136 | 5234 | 0.0265 | -0.0787 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 61.90 | 56.33 | 187 | 7075 | 0.0265 | -0.0503 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 39.80 | 56.33 | 89 | 3393 | 0.0269 | -0.0998 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 89.20 | 56.33 | 191 | 7229 | 0.0269 | -0.0888 |
| MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 80.70 | 56.33 | 212 | 7920 | 0.0269 | -0.0110 |
| MCF 10A-H2B-mCherry | Taxol | 0.01 | 46.60 | 56.33 | 116 | 4538 | 0.0271 | -0.1111 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 58.50 | 56.33 | 179 | 6599 | 0.0271 | -0.0554 |
| MCF 10A-H2B-mCherry | Taxol | 0.017783 | 31.30 | 56.33 | 58 | 2241 | 0.0272 | -0.1976 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 87.50 | 56.33 | 197 | 7334 | 0.0274 | -0.0761 |
| MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 77.30 | 56.33 | 221 | 8135 | 0.0275 | -0.0013 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 85.80 | 56.33 | 203 | 7583 | 0.0276 | -0.0680 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 84.10 | 56.33 | 209 | 7655 | 0.0282 | -0.0543 |