LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 6 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 3. - Dataset (ID:20314)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 41.50 | 56.33 | 150 | 3667 | 0.0417 | -0.0702 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 82.40 | 56.33 | 135 | 7810 | 0.0177 | -0.0692 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 85.80 | 56.33 | 203 | 7583 | 0.0276 | -0.0680 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 58.50 | 56.33 | 227 | 6599 | 0.0325 | -0.0664 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 67.00 | 56.33 | 161 | 7731 | 0.0207 | -0.0654 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 36.40 | 56.33 | 158 | 2958 | 0.0545 | -0.0652 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 38.10 | 56.33 | 158 | 3168 | 0.0508 | -0.0622 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 56.80 | 56.33 | 241 | 6354 | 0.0361 | -0.0617 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 63.60 | 56.33 | 166 | 7339 | 0.0225 | -0.0616 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 84.10 | 56.33 | 136 | 7655 | 0.0181 | -0.0588 |
| MCF 10A-H2B-mCherry | Taxol | 0.01 | 34.70 | 56.33 | 162 | 2720 | 0.0634 | -0.0587 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 33.00 | 56.33 | 109 | 2479 | 0.0453 | -0.0586 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 33.00 | 56.33 | 167 | 2479 | 0.0684 | -0.0561 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 58.50 | 56.33 | 179 | 6599 | 0.0271 | -0.0554 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 60.20 | 56.33 | 179 | 6852 | 0.0265 | -0.0545 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 84.10 | 56.33 | 209 | 7655 | 0.0282 | -0.0543 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 31.30 | 56.33 | 118 | 2241 | 0.0541 | -0.0534 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 55.10 | 56.33 | 250 | 6087 | 0.0393 | -0.0527 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 19.30 | 56.33 | 127 | 1090 | 0.1156 | -0.0526 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 65.30 | 56.33 | 189 | 7570 | 0.0247 | -0.0515 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 61.90 | 56.33 | 187 | 7075 | 0.0265 | -0.0503 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 31.30 | 56.33 | 172 | 2241 | 0.0778 | -0.0493 |
| MCF 10A-H2B-mCherry | Taxol | 0.0031623 | 94.30 | 56.33 | 143 | 6924 | 0.0207 | -0.0492 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 85.80 | 56.33 | 143 | 7583 | 0.0191 | -0.0477 |
| MCF 10A-H2B-mCherry | Taxol | 0.017783 | 22.80 | 56.33 | 151 | 1460 | 0.1060 | -0.0437 |