LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 6 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 3. - Dataset (ID:20314)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 72.20 | 56.33 | 53 | 8053 | 0.0070 | -0.1034 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 68.70 | 56.33 | 177 | 7933 | 0.0201 | -0.1028 |
| MCF 10A-H2B-mCherry | Taxol | 0.01 | 41.50 | 56.33 | 129 | 3667 | 0.0375 | -0.1003 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 65.30 | 56.33 | 177 | 7570 | 0.0214 | -0.0998 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 39.80 | 56.33 | 89 | 3393 | 0.0269 | -0.0998 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 58.50 | 56.33 | 61 | 6599 | 0.0097 | -0.0993 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 73.90 | 56.33 | 109 | 8150 | 0.0137 | -0.0982 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 56.80 | 56.33 | 64 | 6354 | 0.0105 | -0.0966 |
| MCF 10A-H2B-mCherry | Taxol | 0.01 | 39.80 | 56.33 | 133 | 3393 | 0.0415 | -0.0964 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 60.20 | 56.33 | 59 | 6852 | 0.0091 | -0.0957 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 70.50 | 56.33 | 114 | 7990 | 0.0146 | -0.0933 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 38.10 | 56.33 | 95 | 3168 | 0.0307 | -0.0933 |
| MCF 10A-H2B-mCherry | Taxol | 0.01 | 38.10 | 56.33 | 145 | 3168 | 0.0484 | -0.0928 |
| MCF 10A-H2B-mCherry | Taxol | 0.017783 | 24.50 | 56.33 | 121 | 1615 | 0.0765 | -0.0926 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 72.20 | 56.33 | 120 | 8053 | 0.0152 | -0.0917 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 36.40 | 56.33 | 100 | 2958 | 0.0346 | -0.0917 |
| MCF 10A-H2B-mCherry | Dasatinib | 10 | 89.20 | 56.33 | 191 | 7229 | 0.0269 | -0.0888 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 72.20 | 56.33 | 131 | 8053 | 0.0167 | -0.0873 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 58.50 | 56.33 | 125 | 6599 | 0.0194 | -0.0862 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 63.60 | 56.33 | 203 | 7339 | 0.0255 | -0.0856 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 53.40 | 56.33 | 130 | 5809 | 0.0228 | -0.0854 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 34.70 | 56.33 | 103 | 2720 | 0.0393 | -0.0832 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 61.90 | 56.33 | 200 | 7075 | 0.0261 | -0.0829 |
| MCF 10A-H2B-mCherry | Palbociclib | 10 | 95.70 | 27.76 | 204 | 6712 | 0.0305 | -0.0826 |
| MCF 10A-H2B-mCherry | Vorinostat | 10 | 56.80 | 56.33 | 129 | 6354 | 0.0207 | -0.0825 |