LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Neratinib | 1 | 14.50 | 19.50 | 452 | 537 | 0.8420 | 0.4908 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 16.50 | 19.50 | 452 | 626 | 0.7218 | 0.4246 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 18.40 | 19.50 | 470 | 775 | 0.6078 | 0.4848 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 20.40 | 19.50 | 474 | 951 | 0.5005 | 0.4323 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 22.40 | 19.50 | 501 | 1150 | 0.4372 | 0.4252 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 24.30 | 19.50 | 530 | 1322 | 0.4002 | 0.4236 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 26.30 | 19.50 | 535 | 1491 | 0.3581 | 0.4430 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 28.30 | 19.50 | 520 | 1665 | 0.3122 | 0.4239 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 30.30 | 19.50 | 530 | 1887 | 0.2812 | 0.3864 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 32.20 | 19.50 | 532 | 2123 | 0.2509 | 0.3824 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 34.20 | 19.50 | 515 | 2452 | 0.2113 | 0.3741 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 36.20 | 19.50 | 488 | 2641 | 0.1854 | 0.3350 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 38.10 | 19.50 | 493 | 2867 | 0.1726 | 0.3284 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 40.10 | 19.50 | 485 | 3104 | 0.1563 | 0.3143 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 42.10 | 19.50 | 487 | 3461 | 0.1409 | 0.3375 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 44.00 | 19.50 | 496 | 3824 | 0.1302 | 0.3375 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 46.00 | 19.50 | 526 | 4146 | 0.1270 | 0.3356 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 48.00 | 19.50 | 525 | 4441 | 0.1180 | 0.3158 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 50.00 | 19.50 | 529 | 4744 | 0.1113 | 0.3163 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 51.90 | 19.50 | 519 | 4974 | 0.1040 | 0.3220 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 53.90 | 19.50 | 511 | 5154 | 0.0988 | 0.3160 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 55.90 | 19.50 | 517 | 5348 | 0.0964 | 0.3184 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 57.80 | 19.50 | 515 | 5483 | 0.0940 | 0.3166 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 59.80 | 19.50 | 509 | 5578 | 0.0914 | 0.3148 |
| MCF 10A-H2B-mCherry | Neratinib | 1 | 62.80 | 19.50 | 495 | 5586 | 0.0889 | 0.3071 |