LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 92.30 | 19.50 | 2147 | 6153 | 0.3485 | 0.7345 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 94.30 | 19.50 | 2181 | 6154 | 0.3531 | 0.7380 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 2.70 | 19.50 | 199 | 163 | 1.2128 | 0.5171 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 4.60 | 19.50 | 321 | 295 | 1.0886 | 0.4520 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 6.60 | 19.50 | 387 | 390 | 0.9916 | 0.4641 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 8.60 | 19.50 | 425 | 442 | 0.9627 | 0.4794 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 10.60 | 19.50 | 441 | 467 | 0.9439 | 0.5210 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 12.50 | 19.50 | 457 | 495 | 0.9239 | 0.5468 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 14.50 | 19.50 | 489 | 537 | 0.9100 | 0.6024 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 16.50 | 19.50 | 532 | 626 | 0.8507 | 0.6196 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 18.40 | 19.50 | 589 | 775 | 0.7608 | 0.6388 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 20.40 | 19.50 | 642 | 951 | 0.6761 | 0.6152 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 22.40 | 19.50 | 684 | 1150 | 0.5951 | 0.6069 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 24.30 | 19.50 | 725 | 1322 | 0.5486 | 0.6114 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 26.30 | 19.50 | 745 | 1491 | 0.5002 | 0.6170 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 28.30 | 19.50 | 752 | 1665 | 0.4521 | 0.6238 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 30.30 | 19.50 | 772 | 1887 | 0.4093 | 0.6353 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 32.20 | 19.50 | 788 | 2123 | 0.3711 | 0.6340 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 34.20 | 19.50 | 814 | 2452 | 0.3318 | 0.6327 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 36.20 | 19.50 | 836 | 2641 | 0.3164 | 0.6307 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 38.10 | 19.50 | 842 | 2867 | 0.2937 | 0.6250 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 40.10 | 19.50 | 863 | 3104 | 0.2779 | 0.6199 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 42.10 | 19.50 | 873 | 3461 | 0.2521 | 0.6092 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 44.00 | 19.50 | 887 | 3824 | 0.2317 | 0.5985 |
| MCF 10A-H2B-mCherry | Trametinib | 0.031623 | 46.00 | 19.50 | 908 | 4146 | 0.2191 | 0.5962 |