LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 12.50 | 19.50 | 516 | 495 | 1.0421 | 0.5444 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 14.50 | 19.50 | 561 | 537 | 1.0449 | 0.5594 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 16.50 | 19.50 | 626 | 626 | 1.0018 | 0.5550 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 18.40 | 19.50 | 696 | 775 | 0.8990 | 0.5992 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 20.40 | 19.50 | 763 | 951 | 0.8058 | 0.5966 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 22.40 | 19.50 | 862 | 1150 | 0.7524 | 0.6321 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 24.30 | 19.50 | 981 | 1322 | 0.7397 | 0.6617 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 26.30 | 19.50 | 1105 | 1491 | 0.7393 | 0.6571 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 28.30 | 19.50 | 1223 | 1665 | 0.7337 | 0.6639 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 30.30 | 19.50 | 1387 | 1887 | 0.7352 | 0.6777 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 32.20 | 19.50 | 1518 | 2123 | 0.7161 | 0.6859 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 34.20 | 19.50 | 1665 | 2452 | 0.6843 | 0.6764 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 36.20 | 19.50 | 1793 | 2641 | 0.6811 | 0.6738 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 38.10 | 19.50 | 1930 | 2867 | 0.6756 | 0.6832 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 40.10 | 19.50 | 2100 | 3104 | 0.6773 | 0.6900 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 42.10 | 19.50 | 2295 | 3461 | 0.6649 | 0.6942 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 44.00 | 19.50 | 2503 | 3824 | 0.6574 | 0.6897 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 46.00 | 19.50 | 2712 | 4146 | 0.6540 | 0.6945 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 48.00 | 19.50 | 2928 | 4441 | 0.6578 | 0.6985 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 50.00 | 19.50 | 3118 | 4744 | 0.6543 | 0.6968 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 51.90 | 19.50 | 3275 | 4974 | 0.6537 | 0.6969 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 53.90 | 19.50 | 3477 | 5154 | 0.6682 | 0.7086 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 55.90 | 19.50 | 3733 | 5348 | 0.6892 | 0.7138 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 57.80 | 19.50 | 4026 | 5483 | 0.7243 | 0.7285 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 59.80 | 19.50 | 4241 | 5578 | 0.7496 | 0.7374 |