LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Etoposide | 10 | 86.40 | 19.50 | 309 | 6081 | 0.0508 | 0.1579 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 88.40 | 19.50 | 318 | 6064 | 0.0524 | 0.1480 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 90.40 | 19.50 | 317 | 6097 | 0.0521 | 0.1394 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 92.30 | 19.50 | 318 | 6153 | 0.0517 | 0.1389 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 94.30 | 19.50 | 312 | 6154 | 0.0508 | 0.1215 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 2.70 | 19.50 | 211 | 163 | 1.2381 | 0.5116 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 4.60 | 19.50 | 352 | 295 | 1.1821 | 0.4761 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 6.60 | 19.50 | 447 | 390 | 1.1437 | 0.4737 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 8.60 | 19.50 | 481 | 442 | 1.0890 | 0.4584 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 10.60 | 19.50 | 503 | 467 | 1.0781 | 0.4718 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 12.50 | 19.50 | 532 | 495 | 1.0733 | 0.5278 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 14.50 | 19.50 | 576 | 537 | 1.0707 | 0.5675 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 16.50 | 19.50 | 639 | 626 | 1.0258 | 0.6538 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 18.40 | 19.50 | 779 | 775 | 1.0099 | 0.7648 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 20.40 | 19.50 | 941 | 951 | 0.9966 | 0.8286 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 22.40 | 19.50 | 1108 | 1150 | 0.9694 | 0.8493 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 24.30 | 19.50 | 1230 | 1322 | 0.9276 | 0.8466 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 26.30 | 19.50 | 1349 | 1491 | 0.9037 | 0.8493 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 28.30 | 19.50 | 1509 | 1665 | 0.9059 | 0.8602 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 30.30 | 19.50 | 1717 | 1887 | 0.9102 | 0.8593 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 32.20 | 19.50 | 1949 | 2123 | 0.9185 | 0.8749 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 34.20 | 19.50 | 2280 | 2452 | 0.9306 | 0.8956 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 36.20 | 19.50 | 2497 | 2641 | 0.9454 | 0.9070 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 38.10 | 19.50 | 2739 | 2867 | 0.9551 | 0.9067 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 40.10 | 19.50 | 2973 | 3104 | 0.9574 | 0.9165 |