LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 74.60 | 19.50 | 4520 | 5927 | 0.7607 | 0.8029 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 76.60 | 19.50 | 4702 | 5898 | 0.7953 | 0.8136 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 78.50 | 19.50 | 4843 | 5949 | 0.8118 | 0.8189 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 80.50 | 19.50 | 5018 | 6018 | 0.8315 | 0.8227 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 82.50 | 19.50 | 5205 | 6031 | 0.8609 | 0.8315 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 84.40 | 19.50 | 5389 | 6038 | 0.8909 | 0.8408 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 86.40 | 19.50 | 5447 | 6081 | 0.8943 | 0.8274 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 88.40 | 19.50 | 5611 | 6064 | 0.9249 | 0.8407 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 90.40 | 19.50 | 5759 | 6097 | 0.9450 | 0.8290 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 92.30 | 19.50 | 5846 | 6153 | 0.9510 | 0.8379 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 94.30 | 19.50 | 5950 | 6154 | 0.9695 | 0.8391 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 2.70 | 19.50 | 258 | 163 | 1.5425 | 0.6259 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 4.60 | 19.50 | 364 | 295 | 1.2251 | 0.4905 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 6.60 | 19.50 | 431 | 390 | 1.1033 | 0.4524 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 8.60 | 19.50 | 467 | 442 | 1.0577 | 0.4900 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 10.60 | 19.50 | 490 | 467 | 1.0504 | 0.4989 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 12.50 | 19.50 | 510 | 495 | 1.0292 | 0.4948 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 14.50 | 19.50 | 541 | 537 | 1.0073 | 0.5143 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 16.50 | 19.50 | 598 | 626 | 0.9617 | 0.5391 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 18.40 | 19.50 | 668 | 775 | 0.8671 | 0.5377 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 20.40 | 19.50 | 711 | 951 | 0.7570 | 0.5288 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 22.40 | 19.50 | 764 | 1150 | 0.6708 | 0.5132 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 24.30 | 19.50 | 813 | 1322 | 0.6114 | 0.5042 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 26.30 | 19.50 | 837 | 1491 | 0.5591 | 0.5306 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0056667 | 28.30 | 19.50 | 863 | 1665 | 0.5179 | 0.5443 |