LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
Download: Excel (XLSX), Comma-separated (CSV)
| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 62.80 | 19.50 | 4494 | 5586 | 0.7930 | 0.7452 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 64.70 | 19.50 | 4719 | 5643 | 0.8235 | 0.7565 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 66.70 | 19.50 | 4906 | 5728 | 0.8441 | 0.7577 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 68.70 | 19.50 | 5123 | 5743 | 0.8793 | 0.7713 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 70.70 | 19.50 | 5305 | 5784 | 0.9055 | 0.7695 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 72.60 | 19.50 | 5493 | 5854 | 0.9287 | 0.7780 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 74.60 | 19.50 | 5627 | 5927 | 0.9401 | 0.7761 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 76.60 | 19.50 | 5831 | 5898 | 0.9813 | 0.7772 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 78.50 | 19.50 | 5842 | 5949 | 0.9752 | 0.7671 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 80.50 | 19.50 | 5903 | 6018 | 0.9751 | 0.7562 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 82.50 | 19.50 | 5944 | 6031 | 0.9808 | 0.7490 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 84.40 | 19.50 | 5766 | 6038 | 0.9527 | 0.7270 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 86.40 | 19.50 | 5808 | 6081 | 0.9537 | 0.7242 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 88.40 | 19.50 | 5765 | 6064 | 0.9504 | 0.7049 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 90.40 | 19.50 | 5824 | 6097 | 0.9554 | 0.6978 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 92.30 | 19.50 | 5855 | 6153 | 0.9519 | 0.6735 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 94.30 | 19.50 | 5947 | 6154 | 0.9673 | 0.6644 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 2.70 | 19.50 | 269 | 163 | 1.6493 | 0.6654 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 4.60 | 19.50 | 419 | 295 | 1.4357 | 0.5386 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 6.60 | 19.50 | 485 | 390 | 1.2429 | 0.5110 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 8.60 | 19.50 | 539 | 442 | 1.2195 | 0.6216 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 10.60 | 19.50 | 602 | 467 | 1.2880 | 0.6960 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 12.50 | 19.50 | 655 | 495 | 1.3218 | 0.8062 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 14.50 | 19.50 | 735 | 537 | 1.3667 | 0.8635 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0016667 | 16.50 | 19.50 | 857 | 626 | 1.3742 | 0.9183 |