LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 5 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 2. - Dataset (ID:20313)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 88.40 | 19.50 | 1 | 6064 | 0.0002 | -0.2931 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 90.40 | 19.50 | 1 | 6097 | 0.0002 | -0.3005 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 92.30 | 19.50 | 1 | 6153 | 0.0002 | -0.3001 |
| MCF 10A-H2B-mCherry | Taxol | 0.31623 | 94.30 | 19.50 | 1 | 6154 | 0.0002 | -0.2925 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 2.70 | 19.50 | 228 | 163 | 1.3544 | 0.5790 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 4.60 | 19.50 | 341 | 295 | 1.1488 | 0.4754 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 6.60 | 19.50 | 418 | 390 | 1.0696 | 0.4856 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 8.60 | 19.50 | 467 | 442 | 1.0578 | 0.5049 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 10.60 | 19.50 | 491 | 467 | 1.0511 | 0.5043 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 12.50 | 19.50 | 518 | 495 | 1.0452 | 0.5212 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 14.50 | 19.50 | 555 | 537 | 1.0330 | 0.5521 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 16.50 | 19.50 | 623 | 626 | 0.9963 | 0.5822 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 18.40 | 19.50 | 739 | 775 | 0.9541 | 0.6597 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 20.40 | 19.50 | 851 | 951 | 0.8952 | 0.6415 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 22.40 | 19.50 | 977 | 1150 | 0.8505 | 0.6554 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 24.30 | 19.50 | 1077 | 1322 | 0.8152 | 0.6613 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 26.30 | 19.50 | 1186 | 1491 | 0.7957 | 0.6674 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 28.30 | 19.50 | 1312 | 1665 | 0.7881 | 0.6726 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 30.30 | 19.50 | 1471 | 1887 | 0.7799 | 0.6805 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 32.20 | 19.50 | 1637 | 2123 | 0.7715 | 0.6933 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 34.20 | 19.50 | 1815 | 2452 | 0.7413 | 0.6899 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 36.20 | 19.50 | 1974 | 2641 | 0.7478 | 0.6957 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 38.10 | 19.50 | 2124 | 2867 | 0.7412 | 0.7023 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 40.10 | 19.50 | 2328 | 3104 | 0.7501 | 0.6983 |
| MCF 10A-H2B-mCherry | Trametinib | 0.00021667 | 42.10 | 19.50 | 2560 | 3461 | 0.7401 | 0.7126 |