LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Etoposide | 10 | 67.50 | 770.96 | 810 | 9939 | 0.0816 | 0.0135 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 69.70 | 770.96 | 783 | 10312 | 0.0760 | 0.0040 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 71.90 | 770.96 | 794 | 10631 | 0.0747 | 0.0077 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 74.10 | 770.96 | 807 | 10921 | 0.0740 | 0.0118 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 76.40 | 770.96 | 813 | 11184 | 0.0728 | 0.0134 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 78.60 | 770.96 | 802 | 11443 | 0.0701 | 0.0098 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 80.80 | 770.96 | 784 | 11725 | 0.0669 | 0.0042 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 83.10 | 770.96 | 784 | 12002 | 0.0654 | 0.0041 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 85.30 | 770.96 | 775 | 12277 | 0.0631 | 0.0008 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 87.50 | 770.96 | 773 | 12567 | 0.0615 | 0.0006 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 2.90 | 770.96 | 866 | 886 | 0.9785 | 0.9549 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 5.10 | 770.96 | 973 | 984 | 0.9904 | 1.0205 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 7.30 | 770.96 | 1050 | 1067 | 0.9848 | 0.9557 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 9.60 | 770.96 | 1167 | 1178 | 0.9926 | 0.9994 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 11.90 | 770.96 | 1311 | 1319 | 0.9954 | 0.9977 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 14.10 | 770.96 | 1460 | 1478 | 0.9882 | 0.9777 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 16.40 | 770.96 | 1615 | 1625 | 0.9957 | 0.9957 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 18.60 | 770.96 | 1755 | 1786 | 0.9843 | 0.9767 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 20.80 | 770.96 | 1955 | 1959 | 0.9993 | 1.0006 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 23.00 | 770.96 | 2163 | 2193 | 0.9879 | 0.9847 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 25.30 | 770.96 | 2431 | 2456 | 0.9913 | 0.9898 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 27.50 | 770.96 | 2725 | 2754 | 0.9918 | 0.9911 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 29.70 | 770.96 | 3023 | 3022 | 1.0022 | 1.0020 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 31.90 | 770.96 | 3317 | 3294 | 1.0089 | 1.0082 |
| MCF 10A-H2B-mCherry | Neratinib | 0.00043333 | 34.10 | 770.96 | 3603 | 3605 | 1.0013 | 1.0008 |