LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 4 of 15: End-point mean cell counts and mean normalized growth rate inhibition values for biological replicate 1. - Dataset (ID:20312)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Mean Total Cell Count Before Treatment | Mean Total Cell Count After Treatment | Mean Total Control Cell Count | Mean Relative Cell Count | Mean Normalized Growth Rate Inhibition Value |
|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 76.40 | 770.96 | 877 | 11184 | 0.0784 | 0.0140 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 78.60 | 770.96 | 863 | 11443 | 0.0754 | 0.0060 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 80.80 | 770.96 | 838 | 11725 | 0.0714 | -0.0056 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 83.10 | 770.96 | 846 | 12002 | 0.0705 | -0.0080 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 85.30 | 770.96 | 848 | 12277 | 0.0691 | -0.0133 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 87.50 | 770.96 | 862 | 12567 | 0.0687 | -0.0162 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 2.90 | 770.96 | 876 | 886 | 0.9874 | 0.9592 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 5.10 | 770.96 | 976 | 984 | 0.9906 | 0.9634 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 7.30 | 770.96 | 1060 | 1067 | 0.9926 | 0.9695 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 9.60 | 770.96 | 1182 | 1178 | 1.0018 | 1.0021 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 11.90 | 770.96 | 1301 | 1319 | 0.9850 | 0.9591 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 14.10 | 770.96 | 1438 | 1478 | 0.9722 | 0.9393 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 16.40 | 770.96 | 1567 | 1625 | 0.9634 | 0.9286 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 18.60 | 770.96 | 1722 | 1786 | 0.9625 | 0.9340 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 20.80 | 770.96 | 1857 | 1959 | 0.9467 | 0.9165 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 23.00 | 770.96 | 2050 | 2193 | 0.9336 | 0.9075 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 25.30 | 770.96 | 2282 | 2456 | 0.9278 | 0.9093 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 27.50 | 770.96 | 2545 | 2754 | 0.9225 | 0.9109 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 29.70 | 770.96 | 2847 | 3022 | 0.9407 | 0.9358 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 31.90 | 770.96 | 3088 | 3294 | 0.9359 | 0.9346 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 34.10 | 770.96 | 3359 | 3605 | 0.9302 | 0.9330 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 36.40 | 770.96 | 3679 | 3985 | 0.9217 | 0.9293 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 38.60 | 770.96 | 4058 | 4421 | 0.9164 | 0.9292 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 40.80 | 770.96 | 4487 | 4874 | 0.9194 | 0.9356 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.0010833 | 43.00 | 770.96 | 4900 | 5280 | 0.9270 | 0.9441 |