LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 3 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 3. - Dataset (ID:20311)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 1 | 8.76 | 27.76 | 11 | 401 | 0.0274 | -0.2136 | MN20160318_Q01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 8.76 | 27.76 | 925 | 401 | 2.3059 | 1.4843 | MN20160318_Q01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 10.46 | 27.76 | 5 | 438 | 0.0114 | -0.3498 | MN20160318_Q01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 10.46 | 27.76 | 867 | 438 | 1.9766 | 1.3732 | MN20160318_Q01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 10.46 | 27.76 | 74 | 438 | 0.1687 | 0.2792 | MN20160318_Q01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 10.46 | 27.76 | 957 | 438 | 2.1817 | 1.4328 | MN20160318_Q01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 12.17 | 27.76 | 7 | 489 | 0.0143 | -0.2831 | MN20160318_Q01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 12.17 | 27.76 | 894 | 489 | 1.8280 | 1.3138 | MN20160318_Q01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 12.17 | 27.76 | 209 | 489 | 0.4273 | 0.6286 | MN20160318_Q01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 12.17 | 27.76 | 1028 | 489 | 2.1019 | 1.3932 | MN20160318_Q01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 13.87 | 27.76 | 13 | 604 | 0.0215 | -0.1569 | MN20160318_Q01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 13.87 | 27.76 | 895 | 604 | 1.4800 | 1.1844 | MN20160318_Q01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 13.87 | 27.76 | 715 | 604 | 1.1824 | 1.0768 | MN20160318_Q01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 13.87 | 27.76 | 1076 | 604 | 1.7794 | 1.2768 | MN20160318_Q01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 15.58 | 27.76 | 19 | 685 | 0.0277 | -0.0787 | MN20160318_Q01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 15.58 | 27.76 | 950 | 685 | 1.3857 | 1.1461 | MN20160318_Q01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 15.58 | 27.76 | 848 | 685 | 1.2369 | 1.0941 | MN20160318_Q01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 15.58 | 27.76 | 1084 | 685 | 1.5812 | 1.2082 | MN20160318_Q01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 17.28 | 27.76 | 27 | 838 | 0.0322 | -0.0056 | MN20160318_Q01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 17.28 | 27.76 | 918 | 838 | 1.0945 | 1.0371 | MN20160318_Q01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 17.28 | 27.76 | 1029 | 838 | 1.2269 | 1.0849 | MN20160318_Q01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 17.28 | 27.76 | 1171 | 838 | 1.3962 | 1.1405 | MN20160318_Q01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 18.98 | 27.76 | 25 | 941 | 0.0266 | -0.0204 | MN20160318_Q01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 18.98 | 27.76 | 922 | 941 | 0.9797 | 0.9919 | MN20160318_Q01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 18.98 | 27.76 | 976 | 941 | 1.0370 | 1.0144 | MN20160318_Q01 | K06 |