LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 3 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 3. - Dataset (ID:20311)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 15.58 | 27.76 | 17 | 685 | 0.0248 | -0.1006 | MN20160318_Q01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 15.58 | 27.76 | 985 | 685 | 1.4368 | 1.1630 | MN20160318_Q01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 15.58 | 27.76 | 813 | 685 | 1.1859 | 1.0751 | MN20160318_Q01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 15.58 | 27.76 | 1034 | 685 | 1.5082 | 1.1858 | MN20160318_Q01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 15.58 | 27.76 | 14 | 685 | 0.0204 | -0.1375 | MN20160318_Q01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 15.58 | 27.76 | 1175 | 685 | 1.7139 | 1.2470 | MN20160318_Q01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 17.28 | 27.76 | 17 | 838 | 0.0203 | -0.0949 | MN20160318_Q01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 17.28 | 27.76 | 1045 | 838 | 1.2460 | 1.0915 | MN20160318_Q01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 17.28 | 27.76 | 940 | 838 | 1.1208 | 1.0469 | MN20160318_Q01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 17.28 | 27.76 | 993 | 838 | 1.1840 | 1.0699 | MN20160318_Q01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 17.28 | 27.76 | 18 | 838 | 0.0215 | -0.0843 | MN20160318_Q01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 17.28 | 27.76 | 1247 | 838 | 1.4868 | 1.1680 | MN20160318_Q01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 18.98 | 27.76 | 23 | 941 | 0.0244 | -0.0363 | MN20160318_Q01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 18.98 | 27.76 | 1069 | 941 | 1.1359 | 1.0508 | MN20160318_Q01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 18.98 | 27.76 | 1095 | 941 | 1.1635 | 1.0605 | MN20160318_Q01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 18.98 | 27.76 | 1140 | 941 | 1.2113 | 1.0769 | MN20160318_Q01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 18.98 | 27.76 | 39 | 941 | 0.0414 | 0.0692 | MN20160318_Q01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 18.98 | 27.76 | 1359 | 941 | 1.4440 | 1.1499 | MN20160318_Q01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 20.68 | 27.76 | 25 | 1119 | 0.0223 | -0.0194 | MN20160318_Q01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 20.68 | 27.76 | 1188 | 1119 | 1.0617 | 1.0226 | MN20160318_Q01 | E20 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 20.68 | 27.76 | 1105 | 1119 | 0.9875 | 0.9953 | MN20160318_Q01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 20.68 | 27.76 | 1146 | 1119 | 1.0241 | 1.0090 | MN20160318_Q01 | H05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 20.68 | 27.76 | 56 | 1119 | 0.0500 | 0.1406 | MN20160318_Q01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 20.68 | 27.76 | 1338 | 1119 | 1.1957 | 1.0682 | MN20160318_Q01 | I21 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 22.39 | 27.76 | 22 | 1305 | 0.0168 | -0.0410 | MN20160318_Q01 | E20 |