LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 3 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 3. - Dataset (ID:20311)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 1 | 6.06 | 84.90 | 1 | 365 | 0.0027 | -0.8787 | MN20160318_Q02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 6.06 | 84.90 | 940 | 365 | 2.5722 | 2.1323 | MN20160318_Q02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 7.77 | 84.90 | 1 | 411 | 0.0024 | -0.8579 | MN20160318_Q02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 7.77 | 84.90 | 1069 | 411 | 2.5995 | 2.0430 | MN20160318_Q02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 7.77 | 84.90 | 2 | 411 | 0.0049 | -0.8073 | MN20160318_Q02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 7.77 | 84.90 | 1034 | 411 | 2.5144 | 1.9988 | MN20160318_Q02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 9.47 | 84.90 | 1 | 447 | 0.0022 | -0.8431 | MN20160318_Q02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 9.47 | 84.90 | 1124 | 447 | 2.5121 | 1.9367 | MN20160318_Q02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 9.47 | 84.90 | 2 | 447 | 0.0045 | -0.7905 | MN20160318_Q02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 9.47 | 84.90 | 1050 | 447 | 2.3467 | 1.8545 | MN20160318_Q02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 11.18 | 84.90 | 1 | 492 | 0.0020 | -0.8265 | MN20160318_Q02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 11.18 | 84.90 | 1175 | 492 | 2.3865 | 1.8183 | MN20160318_Q02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 11.18 | 84.90 | 15 | 492 | 0.0305 | -0.4952 | MN20160318_Q02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 11.18 | 84.90 | 1146 | 492 | 2.3276 | 1.7907 | MN20160318_Q02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 12.88 | 84.90 | 3 | 531 | 0.0056 | -0.7174 | MN20160318_Q02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 12.88 | 84.90 | 1233 | 531 | 2.3220 | 1.7502 | MN20160318_Q02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 12.88 | 84.90 | 25 | 531 | 0.0471 | -0.3701 | MN20160318_Q02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 12.88 | 84.90 | 1187 | 531 | 2.2354 | 1.7109 | MN20160318_Q02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 14.58 | 84.90 | 185 | 663 | 0.2789 | 0.3003 | MN20160318_Q02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 14.58 | 84.90 | 1306 | 663 | 1.9686 | 1.5131 | MN20160318_Q02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 14.58 | 84.90 | 224 | 663 | 0.3377 | 0.3869 | MN20160318_Q02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 14.58 | 84.90 | 1233 | 663 | 1.8586 | 1.4648 | MN20160318_Q02 | I10 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 16.29 | 84.90 | 367 | 766 | 0.4786 | 0.5857 | MN20160318_Q02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 16.29 | 84.90 | 1305 | 766 | 1.7018 | 1.3646 | MN20160318_Q02 | I09 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 16.29 | 84.90 | 328 | 766 | 0.4277 | 0.5306 | MN20160318_Q02 | I10 |