LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 3 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 3. - Dataset (ID:20311)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 8.76 | 27.76 | 15 | 401 | 0.0374 | -0.1476 | MN20160318_Q01 | L03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 8.76 | 27.76 | 897 | 401 | 2.2361 | 1.4645 | MN20160318_Q01 | L03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 8.76 | 27.76 | 2 | 401 | 0.0050 | -0.4947 | MN20160318_Q01 | L05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 8.76 | 27.76 | 940 | 401 | 2.3433 | 1.4947 | MN20160318_Q01 | L05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 10.46 | 27.76 | 64 | 438 | 0.1459 | 0.2334 | MN20160318_Q01 | L03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 10.46 | 27.76 | 948 | 438 | 2.1612 | 1.4271 | MN20160318_Q01 | L03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 10.46 | 27.76 | 17 | 438 | 0.0388 | -0.1159 | MN20160318_Q01 | L05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 10.46 | 27.76 | 1001 | 438 | 2.2820 | 1.4605 | MN20160318_Q01 | L05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 12.17 | 27.76 | 92 | 489 | 0.1881 | 0.3358 | MN20160318_Q01 | L03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 12.17 | 27.76 | 996 | 489 | 2.0365 | 1.3750 | MN20160318_Q01 | L03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 12.17 | 27.76 | 89 | 489 | 0.1820 | 0.3251 | MN20160318_Q01 | L05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 12.17 | 27.76 | 1045 | 489 | 2.1367 | 1.4027 | MN20160318_Q01 | L05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 13.87 | 27.76 | 354 | 604 | 0.5854 | 0.7730 | MN20160318_Q01 | L03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 13.87 | 27.76 | 1064 | 604 | 1.7595 | 1.2711 | MN20160318_Q01 | L03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 13.87 | 27.76 | 404 | 604 | 0.6681 | 0.8265 | MN20160318_Q01 | L05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 13.87 | 27.76 | 1111 | 604 | 1.8372 | 1.2933 | MN20160318_Q01 | L05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 15.58 | 27.76 | 749 | 685 | 1.0925 | 1.0386 | MN20160318_Q01 | L03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 15.58 | 27.76 | 1015 | 685 | 1.4805 | 1.1770 | MN20160318_Q01 | L03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 15.58 | 27.76 | 657 | 685 | 0.9583 | 0.9817 | MN20160318_Q01 | L05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 15.58 | 27.76 | 1163 | 685 | 1.6964 | 1.2420 | MN20160318_Q01 | L05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 17.28 | 27.76 | 915 | 838 | 1.0910 | 1.0357 | MN20160318_Q01 | L03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 17.28 | 27.76 | 1084 | 838 | 1.2925 | 1.1071 | MN20160318_Q01 | L03 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 17.28 | 27.76 | 928 | 838 | 1.1065 | 1.0416 | MN20160318_Q01 | L05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 17.28 | 27.76 | 1179 | 838 | 1.4057 | 1.1434 | MN20160318_Q01 | L05 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 18.98 | 27.76 | 956 | 941 | 1.0158 | 1.0062 | MN20160318_Q01 | L03 |