LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 3 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 3. - Dataset (ID:20311)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 7.06 | 27.76 | 750 | 360 | 2.0833 | 1.4392 | MN20160318_Q01 | H06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 7.06 | 27.76 | 10 | 360 | 0.0278 | -0.2413 | MN20160318_Q01 | M14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 7.06 | 27.76 | 938 | 360 | 2.6056 | 1.5914 | MN20160318_Q01 | M14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 8.76 | 27.76 | 1 | 401 | 0.0025 | -0.5779 | MN20160318_Q01 | H06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 8.76 | 27.76 | 832 | 401 | 2.0741 | 1.4169 | MN20160318_Q01 | H06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 8.76 | 27.76 | 20 | 401 | 0.0499 | -0.0816 | MN20160318_Q01 | M14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 8.76 | 27.76 | 996 | 401 | 2.4829 | 1.5324 | MN20160318_Q01 | M14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 10.46 | 27.76 | 103 | 438 | 0.2348 | 0.3900 | MN20160318_Q01 | H06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 10.46 | 27.76 | 899 | 438 | 2.0495 | 1.3949 | MN20160318_Q01 | H06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 10.46 | 27.76 | 28 | 438 | 0.0638 | 0.0022 | MN20160318_Q01 | M14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 10.46 | 27.76 | 1048 | 438 | 2.3892 | 1.4890 | MN20160318_Q01 | M14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 12.17 | 27.76 | 120 | 489 | 0.2454 | 0.4243 | MN20160318_Q01 | H06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 12.17 | 27.76 | 952 | 489 | 1.9465 | 1.3492 | MN20160318_Q01 | H06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 12.17 | 27.76 | 42 | 489 | 0.0859 | 0.1052 | MN20160318_Q01 | M14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 12.17 | 27.76 | 969 | 489 | 1.9813 | 1.3593 | MN20160318_Q01 | M14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 13.87 | 27.76 | 327 | 604 | 0.5408 | 0.7417 | MN20160318_Q01 | H06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 13.87 | 27.76 | 1018 | 604 | 1.6834 | 1.2486 | MN20160318_Q01 | H06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 13.87 | 27.76 | 36 | 604 | 0.0595 | 0.0602 | MN20160318_Q01 | M14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 13.87 | 27.76 | 1078 | 604 | 1.7827 | 1.2778 | MN20160318_Q01 | M14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 15.58 | 27.76 | 344 | 685 | 0.5018 | 0.7230 | MN20160318_Q01 | H06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 15.58 | 27.76 | 1055 | 685 | 1.5389 | 1.1953 | MN20160318_Q01 | H06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 15.58 | 27.76 | 45 | 685 | 0.0656 | 0.1101 | MN20160318_Q01 | M14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 15.58 | 27.76 | 1048 | 685 | 1.5287 | 1.1921 | MN20160318_Q01 | M14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 17.28 | 27.76 | 670 | 838 | 0.7988 | 0.9107 | MN20160318_Q01 | H06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 17.28 | 27.76 | 1000 | 838 | 1.1923 | 1.0728 | MN20160318_Q01 | H06 |