LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 3 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 3. - Dataset (ID:20311)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 10.46 | 27.76 | 947 | 438 | 2.1589 | 1.4264 | MN20160318_Q01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 10.46 | 27.76 | 30 | 438 | 0.0684 | 0.0197 | MN20160318_Q01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 10.46 | 27.76 | 1103 | 438 | 2.5146 | 1.5211 | MN20160318_Q01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 12.17 | 27.76 | 1 | 489 | 0.0020 | -0.5520 | MN20160318_Q01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 12.17 | 27.76 | 985 | 489 | 2.0140 | 1.3686 | MN20160318_Q01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 12.17 | 27.76 | 34 | 489 | 0.0695 | 0.0502 | MN20160318_Q01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 12.17 | 27.76 | 1056 | 489 | 2.1592 | 1.4088 | MN20160318_Q01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 13.87 | 27.76 | 1 | 604 | 0.0017 | -0.5265 | MN20160318_Q01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 13.87 | 27.76 | 1027 | 604 | 1.6983 | 1.2531 | MN20160318_Q01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 13.87 | 27.76 | 51 | 604 | 0.0843 | 0.1466 | MN20160318_Q01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 13.87 | 27.76 | 1249 | 604 | 2.0654 | 1.3545 | MN20160318_Q01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 15.58 | 27.76 | 1 | 685 | 0.0015 | -0.5125 | MN20160318_Q01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 15.58 | 27.76 | 1089 | 685 | 1.5885 | 1.2104 | MN20160318_Q01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 15.58 | 27.76 | 84 | 685 | 0.1225 | 0.2704 | MN20160318_Q01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 15.58 | 27.76 | 1358 | 685 | 1.9808 | 1.3184 | MN20160318_Q01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 17.28 | 27.76 | 118 | 838 | 0.1407 | 0.3422 | MN20160318_Q01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 17.28 | 27.76 | 1169 | 838 | 1.3938 | 1.1397 | MN20160318_Q01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 17.28 | 27.76 | 97 | 838 | 0.1157 | 0.2898 | MN20160318_Q01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 17.28 | 27.76 | 1437 | 838 | 1.7133 | 1.2314 | MN20160318_Q01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 18.98 | 27.76 | 162 | 941 | 0.1721 | 0.4149 | MN20160318_Q01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 18.98 | 27.76 | 1288 | 941 | 1.3685 | 1.1273 | MN20160318_Q01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 18.98 | 27.76 | 130 | 941 | 0.1381 | 0.3549 | MN20160318_Q01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 18.98 | 27.76 | 1546 | 941 | 1.6427 | 1.2051 | MN20160318_Q01 | M13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 20.68 | 27.76 | 508 | 1119 | 0.4540 | 0.7247 | MN20160318_Q01 | H11 |
| MCF 10A-H2B-mCherry | Trametinib | 0.001 | 20.68 | 27.76 | 1427 | 1119 | 1.2752 | 1.0933 | MN20160318_Q01 | H11 |