LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 3 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 3. - Dataset (ID:20311)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 4.36 | 84.90 | 1 | 322 | 0.0031 | -0.9004 | MN20160318_Q02 | N12 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 4.36 | 84.90 | 756 | 322 | 2.3437 | 2.1124 | MN20160318_Q02 | N12 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 6.06 | 84.90 | 1 | 365 | 0.0027 | -0.8787 | MN20160318_Q02 | G13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 6.06 | 84.90 | 723 | 365 | 1.9784 | 1.7652 | MN20160318_Q02 | G13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 6.06 | 84.90 | 1 | 365 | 0.0027 | -0.8787 | MN20160318_Q02 | K07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 6.06 | 84.90 | 899 | 365 | 2.4600 | 2.0667 | MN20160318_Q02 | K07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 6.06 | 84.90 | 1 | 365 | 0.0027 | -0.8787 | MN20160318_Q02 | N12 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 6.06 | 84.90 | 827 | 365 | 2.2629 | 1.9475 | MN20160318_Q02 | N12 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 7.77 | 84.90 | 1 | 411 | 0.0024 | -0.8579 | MN20160318_Q02 | G13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 7.77 | 84.90 | 811 | 411 | 1.9721 | 1.6953 | MN20160318_Q02 | G13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 7.77 | 84.90 | 1 | 411 | 0.0024 | -0.8579 | MN20160318_Q02 | K07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 7.77 | 84.90 | 990 | 411 | 2.4074 | 1.9421 | MN20160318_Q02 | K07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 7.77 | 84.90 | 1 | 411 | 0.0024 | -0.8579 | MN20160318_Q02 | N12 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 7.77 | 84.90 | 909 | 411 | 2.2104 | 1.8338 | MN20160318_Q02 | N12 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 9.47 | 84.90 | 1 | 447 | 0.0022 | -0.8431 | MN20160318_Q02 | G13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 9.47 | 84.90 | 865 | 447 | 1.9333 | 1.6328 | MN20160318_Q02 | G13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 9.47 | 84.90 | 1 | 447 | 0.0022 | -0.8431 | MN20160318_Q02 | K07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 9.47 | 84.90 | 1050 | 447 | 2.3467 | 1.8545 | MN20160318_Q02 | K07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 9.47 | 84.90 | 1 | 447 | 0.0022 | -0.8431 | MN20160318_Q02 | N12 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 9.47 | 84.90 | 964 | 447 | 2.1545 | 1.7545 | MN20160318_Q02 | N12 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 11.18 | 84.90 | 1 | 492 | 0.0020 | -0.8265 | MN20160318_Q02 | G13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 11.18 | 84.90 | 912 | 492 | 1.8523 | 1.5503 | MN20160318_Q02 | G13 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 11.18 | 84.90 | 3 | 492 | 0.0061 | -0.7324 | MN20160318_Q02 | K07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 11.18 | 84.90 | 1147 | 492 | 2.3296 | 1.7917 | MN20160318_Q02 | K07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 11.18 | 84.90 | 1 | 492 | 0.0020 | -0.8265 | MN20160318_Q02 | N12 |