LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 2 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 2. - Dataset (ID:20310)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 1 | 84.06 | 21.74 | 1231 | 6152 | 0.2001 | 0.6415 | MN20160310_N01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 84.06 | 21.74 | 1241 | 6152 | 0.2017 | 0.6431 | MN20160310_N01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 86.03 | 21.74 | 526 | 6155 | 0.0855 | 0.4787 | MN20160310_N01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 86.03 | 21.74 | 1035 | 6155 | 0.1682 | 0.6068 | MN20160310_N01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 86.03 | 21.74 | 1264 | 6155 | 0.2054 | 0.6467 | MN20160310_N01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 86.03 | 21.74 | 1279 | 6155 | 0.2078 | 0.6491 | MN20160310_N01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 88.00 | 21.74 | 510 | 6081 | 0.0839 | 0.4743 | MN20160310_N01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 88.00 | 21.74 | 1023 | 6081 | 0.1682 | 0.6062 | MN20160310_N01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 88.00 | 21.74 | 1235 | 6081 | 0.2031 | 0.6438 | MN20160310_N01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 88.00 | 21.74 | 1248 | 6081 | 0.2052 | 0.6459 | MN20160310_N01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 89.97 | 21.74 | 543 | 6084 | 0.0892 | 0.4857 | MN20160310_N01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 89.97 | 21.74 | 1029 | 6084 | 0.1691 | 0.6072 | MN20160310_N01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 89.97 | 21.74 | 1233 | 6084 | 0.2027 | 0.6434 | MN20160310_N01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 89.97 | 21.74 | 1245 | 6084 | 0.2046 | 0.6454 | MN20160310_N01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 91.94 | 21.74 | 576 | 6121 | 0.0941 | 0.4959 | MN20160310_N01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 91.94 | 21.74 | 1044 | 6121 | 0.1705 | 0.6093 | MN20160310_N01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 91.94 | 21.74 | 1234 | 6121 | 0.2016 | 0.6427 | MN20160310_N01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 91.94 | 21.74 | 1247 | 6121 | 0.2037 | 0.6448 | MN20160310_N01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 93.92 | 21.74 | 609 | 6070 | 0.1003 | 0.5071 | MN20160310_N01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 93.92 | 21.74 | 1055 | 6070 | 0.1738 | 0.6125 | MN20160310_N01 | E15 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 93.92 | 21.74 | 1254 | 6070 | 0.2066 | 0.6472 | MN20160310_N01 | K06 |
| MCF 10A-H2B-mCherry | Trametinib | 1 | 93.92 | 21.74 | 1262 | 6070 | 0.2079 | 0.6485 | MN20160310_N01 | K06 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 2.24 | 21.74 | 1 | 183 | 0.0054 | -0.6323 | MN20160310_N01 | C12 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 2.24 | 21.74 | 340 | 183 | 1.8521 | 1.4434 | MN20160310_N01 | C12 |
| MCF 10A-H2B-mCherry | Vorinostat | 0.0033333 | 2.24 | 21.74 | 13 | 183 | 0.0708 | -0.1539 | MN20160310_N01 | H03 |