LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 2 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 2. - Dataset (ID:20310)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 4.24 | 21.74 | 1 | 317 | 0.0031 | -0.5487 | MN20160310_N01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 4.24 | 21.74 | 649 | 317 | 2.0423 | 1.4053 | MN20160310_N01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 4.24 | 21.74 | 1 | 317 | 0.0031 | -0.5487 | MN20160310_N01 | H10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 4.24 | 21.74 | 746 | 317 | 2.3475 | 1.4935 | MN20160310_N01 | H10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 6.21 | 21.74 | 1 | 392 | 0.0026 | -0.5219 | MN20160310_N01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 6.21 | 21.74 | 750 | 392 | 1.9133 | 1.3365 | MN20160310_N01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 6.21 | 21.74 | 1 | 392 | 0.0026 | -0.5219 | MN20160310_N01 | H10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 6.21 | 21.74 | 837 | 392 | 2.1352 | 1.3988 | MN20160310_N01 | H10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 8.19 | 21.74 | 1 | 439 | 0.0023 | -0.5082 | MN20160310_N01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 8.19 | 21.74 | 809 | 439 | 1.8392 | 1.3016 | MN20160310_N01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 8.19 | 21.74 | 3 | 439 | 0.0068 | -0.3665 | MN20160310_N01 | H10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 8.19 | 21.74 | 899 | 439 | 2.0438 | 1.3582 | MN20160310_N01 | H10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 10.16 | 21.74 | 7 | 463 | 0.0151 | -0.2264 | MN20160310_N01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 10.16 | 21.74 | 838 | 463 | 1.8074 | 1.2870 | MN20160310_N01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 10.16 | 21.74 | 16 | 463 | 0.0345 | -0.0671 | MN20160310_N01 | H10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 10.16 | 21.74 | 937 | 463 | 2.0210 | 1.3455 | MN20160310_N01 | H10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 12.13 | 21.74 | 11 | 496 | 0.0222 | -0.1401 | MN20160310_N01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 12.13 | 21.74 | 876 | 496 | 1.7649 | 1.2683 | MN20160310_N01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 12.13 | 21.74 | 33 | 496 | 0.0665 | 0.0969 | MN20160310_N01 | H10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 12.13 | 21.74 | 960 | 496 | 1.9341 | 1.3148 | MN20160310_N01 | H10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 14.10 | 21.74 | 44 | 540 | 0.0813 | 0.1642 | MN20160310_N01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 14.10 | 21.74 | 913 | 540 | 1.6878 | 1.2390 | MN20160310_N01 | D06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 14.10 | 21.74 | 56 | 540 | 0.1035 | 0.2264 | MN20160310_N01 | H10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 14.10 | 21.74 | 1032 | 540 | 1.9078 | 1.2990 | MN20160310_N01 | H10 |
| MCF 10A-H2B-mCherry | Trametinib | 0.31623 | 16.07 | 21.74 | 121 | 597 | 0.2024 | 0.4319 | MN20160310_N01 | D06 |