LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 2 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 2. - Dataset (ID:20310)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 91.94 | 21.74 | 4259 | 6121 | 0.6957 | 0.9128 | MN20160310_N01 | H06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 91.94 | 21.74 | 304 | 6121 | 0.0497 | 0.3829 | MN20160310_N01 | M14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 91.94 | 21.74 | 3962 | 6121 | 0.6472 | 0.8959 | MN20160310_N01 | M14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 93.92 | 21.74 | 4381 | 6070 | 0.7218 | 0.9213 | MN20160310_N01 | H06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 93.92 | 21.74 | 4391 | 6070 | 0.7234 | 0.9219 | MN20160310_N01 | H06 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 93.92 | 21.74 | 383 | 6070 | 0.0631 | 0.4235 | MN20160310_N01 | M14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.01 | 93.92 | 21.74 | 4066 | 6070 | 0.6699 | 0.9038 | MN20160310_N01 | M14 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 2.24 | 21.74 | 1 | 183 | 0.0054 | -0.6323 | MN20160310_N01 | D08 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 2.24 | 21.74 | 297 | 183 | 1.6179 | 1.3384 | MN20160310_N01 | D08 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 2.24 | 21.74 | 1 | 183 | 0.0054 | -0.6323 | MN20160310_N01 | N22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 2.24 | 21.74 | 586 | 183 | 3.1922 | 1.9161 | MN20160310_N01 | N22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 4.24 | 21.74 | 1 | 317 | 0.0031 | -0.5487 | MN20160310_N01 | D08 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 4.24 | 21.74 | 610 | 317 | 1.9195 | 1.3671 | MN20160310_N01 | D08 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 4.24 | 21.74 | 1 | 317 | 0.0031 | -0.5487 | MN20160310_N01 | N22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 4.24 | 21.74 | 674 | 317 | 2.1209 | 1.4289 | MN20160310_N01 | N22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 6.21 | 21.74 | 1 | 392 | 0.0026 | -0.5219 | MN20160310_N01 | D08 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 6.21 | 21.74 | 716 | 392 | 1.8265 | 1.3106 | MN20160310_N01 | D08 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 6.21 | 21.74 | 1 | 392 | 0.0026 | -0.5219 | MN20160310_N01 | N22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 6.21 | 21.74 | 732 | 392 | 1.8673 | 1.3229 | MN20160310_N01 | N22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 8.19 | 21.74 | 1 | 439 | 0.0023 | -0.5082 | MN20160310_N01 | D08 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 8.19 | 21.74 | 786 | 439 | 1.7869 | 1.2863 | MN20160310_N01 | D08 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 8.19 | 21.74 | 3 | 439 | 0.0068 | -0.3665 | MN20160310_N01 | N22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 8.19 | 21.74 | 797 | 439 | 1.8120 | 1.2937 | MN20160310_N01 | N22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 10.16 | 21.74 | 3 | 463 | 0.0065 | -0.3615 | MN20160310_N01 | D08 |
| MCF 10A-H2B-mCherry | Trametinib | 0.017783 | 10.16 | 21.74 | 821 | 463 | 1.7708 | 1.2764 | MN20160310_N01 | D08 |