LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 2 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 2. - Dataset (ID:20310)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 18.82 | 17.25 | 133 | 800 | 0.1662 | 0.4462 | MN20160310_N02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 18.82 | 17.25 | 1040 | 800 | 1.2992 | 1.0968 | MN20160310_N02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 18.82 | 17.25 | 1 | 800 | 0.0012 | -0.4022 | MN20160310_N02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 18.82 | 17.25 | 1193 | 800 | 1.4903 | 1.1495 | MN20160310_N02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 20.79 | 17.25 | 268 | 1001 | 0.2676 | 0.5970 | MN20160310_N02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 20.79 | 17.25 | 1066 | 1001 | 1.0643 | 1.0214 | MN20160310_N02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 20.79 | 17.25 | 1 | 1001 | 0.0010 | -0.3849 | MN20160310_N02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 20.79 | 17.25 | 1220 | 1001 | 1.2180 | 1.0685 | MN20160310_N02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 22.76 | 17.25 | 318 | 1193 | 0.2664 | 0.6108 | MN20160310_N02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 22.76 | 17.25 | 1065 | 1193 | 0.8923 | 0.9631 | MN20160310_N02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 22.76 | 17.25 | 1 | 1193 | 0.0008 | -0.3725 | MN20160310_N02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 22.76 | 17.25 | 1237 | 1193 | 1.0364 | 1.0117 | MN20160310_N02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 24.73 | 17.25 | 347 | 1290 | 0.2690 | 0.6196 | MN20160310_N02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 24.73 | 17.25 | 1078 | 1290 | 0.8355 | 0.9431 | MN20160310_N02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 24.73 | 17.25 | 1 | 1290 | 0.0008 | -0.3672 | MN20160310_N02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 24.73 | 17.25 | 1224 | 1290 | 0.9487 | 0.9831 | MN20160310_N02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 26.70 | 17.25 | 419 | 1466 | 0.2857 | 0.6449 | MN20160310_N02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 26.70 | 17.25 | 1055 | 1466 | 0.7193 | 0.8998 | MN20160310_N02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 26.70 | 17.25 | 1 | 1466 | 0.0007 | -0.3587 | MN20160310_N02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 26.70 | 17.25 | 1206 | 1466 | 0.8223 | 0.9399 | MN20160310_N02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 28.67 | 17.25 | 456 | 1653 | 0.2758 | 0.6446 | MN20160310_N02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 28.67 | 17.25 | 1056 | 1653 | 0.6388 | 0.8684 | MN20160310_N02 | F07 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 28.67 | 17.25 | 2 | 1653 | 0.0012 | -0.2792 | MN20160310_N02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 28.67 | 17.25 | 1245 | 1653 | 0.7531 | 0.9157 | MN20160310_N02 | J22 |
| MCF 10A-H2B-mCherry | Trametinib | 0.1 | 30.64 | 17.25 | 544 | 1887 | 0.2882 | 0.6644 | MN20160310_N02 | F07 |