LINCS MCF 10A Common Project: Rolling-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 2 of 15: End-point cell counts and normalized growth rate inhibition values for all technical replicates of biological replicate 2. - Dataset (ID:20310)
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| Cell | Small Molecule | Small Mol Concentration (uM) | Time Point (hr) | Total Cell Count Before Treatment | Total Cell Count After Treatment | Total Control Cell Count | Relative Cell Count | Normalized Growth Rate Inhibition Value | Assay Plate | Assay Well |
|---|---|---|---|---|---|---|---|---|---|---|
| MCF 10A-H2B-mCherry | Taxol | 0.01 | 54.27 | 17.25 | 1 | 4884 | 0.0002 | -0.2951 | MN20160310_N02 | G22 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 76.18 | 21.74 | 1 | 6114 | 0.0002 | -0.3151 | MN20160310_N01 | L09 |
| MCF 10A-H2B-mCherry | Taxol | 0.0018 | 71.03 | 17.25 | 1 | 5367 | 0.0002 | -0.2910 | MN20160310_N02 | L05 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 26.70 | 17.25 | 1 | 1466 | 0.0007 | -0.3587 | MN20160310_N02 | F18 |
| MCF 10A-H2B-mCherry | Trametinib | 0.003 | 18.82 | 17.25 | 1 | 800 | 0.0012 | -0.4022 | MN20160310_N02 | N12 |
| MCF 10A-H2B-mCherry | Neratinib | 0.031623 | 2.24 | 21.74 | 1 | 183 | 0.0054 | -0.6323 | MN20160310_N01 | I06 |
| MCF 10A-H2B-mCherry | Taxol | 0.1 | 44.42 | 17.25 | 1 | 3895 | 0.0003 | -0.3053 | MN20160310_N02 | E20 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.0033333 | 28.67 | 17.25 | 1 | 1653 | 0.0006 | -0.3512 | MN20160310_N02 | K13 |
| MCF 10A-H2B-mCherry | Taxol | 0.031623 | 69.06 | 17.25 | 1 | 5242 | 0.0002 | -0.2920 | MN20160310_N02 | M09 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 29.86 | 21.74 | 1 | 1887 | 0.0005 | -0.3801 | MN20160310_N01 | D13 |
| MCF 10A-H2B-mCherry | Taxol | 0.0002 | 60.18 | 17.25 | 1 | 5031 | 0.0002 | -0.2938 | MN20160310_N02 | D13 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 26.70 | 17.25 | 1 | 1466 | 0.0007 | -0.3587 | MN20160310_N02 | L13 |
| MCF 10A-H2B-mCherry | Taxol | 0.00013333 | 36.54 | 17.25 | 1 | 2679 | 0.0004 | -0.3238 | MN20160310_N02 | N13 |
| MCF 10A-H2B-mCherry | Neratinib | 3.1623 | 31.83 | 21.74 | 1 | 2110 | 0.0005 | -0.3728 | MN20160310_N01 | D13 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 76.94 | 17.25 | 1 | 5681 | 0.0002 | -0.2886 | MN20160310_N02 | J11 |
| MCF 10A-H2B-mCherry | Etoposide | 0.056667 | 5.03 | 17.25 | 1 | 273 | 0.0037 | -0.5106 | MN20160310_N02 | F14 |
| MCF 10A-H2B-mCherry | Taxol | 0.00013333 | 40.48 | 17.25 | 1 | 3125 | 0.0003 | -0.3159 | MN20160310_N02 | N13 |
| MCF 10A-H2B-mCherry | Palbociclib | 0.17783 | 6.21 | 21.74 | 1 | 392 | 0.0026 | -0.5219 | MN20160310_N01 | J09 |
| MCF 10A-H2B-mCherry | Taxol | 0.0002 | 8.98 | 17.25 | 1 | 445 | 0.0022 | -0.4552 | MN20160310_N02 | D13 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 28.67 | 17.25 | 1 | 1653 | 0.0006 | -0.3512 | MN20160310_N02 | F18 |
| MCF 10A-H2B-mCherry | Taxol | 0.0056234 | 76.94 | 17.25 | 1 | 5681 | 0.0002 | -0.2886 | MN20160310_N02 | J11 |
| MCF 10A-H2B-mCherry | Etoposide | 10 | 2.24 | 21.74 | 1 | 183 | 0.0054 | -0.6323 | MN20160310_N01 | J18 |
| MCF 10A-H2B-mCherry | Taxol | 0.1 | 36.54 | 17.25 | 1 | 2679 | 0.0004 | -0.3238 | MN20160310_N02 | C06 |
| MCF 10A-H2B-mCherry | Dasatinib | 1.7783 | 30.64 | 17.25 | 1 | 1887 | 0.0005 | -0.3433 | MN20160310_N02 | L16 |
| MCF 10A-H2B-mCherry | Taxol | 0.017783 | 94.68 | 17.25 | 1 | 6239 | 0.0002 | -0.2847 | MN20160310_N02 | N20 |