LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 9 of 9: Calculated dose-response metrics for biological replicate 3 - Dataset (ID:20286)
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| Cell | Small Molecule | GR50 | GEC50 | GRmax | GRinf | GR Hill Coefficient | GR_AOC | GR r2 |
|---|---|---|---|---|---|---|---|---|
| MCF 10A | Taxol | 0.0023 | 0.0031 | -0.3165 | -0.3042 | 1.6318 | 0.6752 | 0.9981 |
| MCF 10A | Taxol | 0.0024 | 0.0031 | -0.2858 | -0.2644 | 1.5756 | 0.6493 | 0.9955 |
| MCF 10A-H2B-mCherry | Taxol | 0.0022 | 0.0028 | -0.2604 | -0.2256 | 1.5275 | 0.6469 | 0.9949 |
| MCF 10A | Taxol | 0.0022 | 0.0028 | -0.2271 | -0.2020 | 1.4423 | 0.6300 | 0.9906 |
| MCF 10A | Dasatinib | 0.1551 | 0.1892 | -0.1852 | -0.1185 | 1.0689 | 0.4887 | 0.9813 |
| MCF 10A | Dasatinib | 0.1701 | 0.2304 | -0.1347 | -0.1314 | 0.7679 | 0.4692 | 0.9752 |
| MCF 10A | Neratinib | 0.0827 | 0.0877 | -0.0628 | -0.0389 | 1.2792 | 0.4175 | 0.9960 |
| MCF 10A | Neratinib | 0.1195 | 0.1285 | -0.0528 | -0.0545 | 1.4275 | 0.3770 | 0.9977 |
| MCF 10A | Neratinib | 0.0875 | 0.0911 | -0.0521 | -0.0308 | 1.4915 | 0.4116 | 0.9975 |
| MCF 10A | Dasatinib | 0.3035 | 0.4514 | -0.0441 | -0.1524 | 0.6704 | 0.4089 | 0.9722 |
| MCF 10A | Vorinostat | 0.9957 | 1.1901 | -0.0328 | -0.1305 | 1.2999 | 0.3098 | 0.9944 |
| MCF 10A | Etoposide | 0.3048 | 0.3297 | -0.0213 | -0.0568 | 1.3677 | 0.3947 | 0.9937 |
| MCF 10A | Vorinostat | 0.9306 | 1.0389 | -0.0111 | -0.0774 | 1.3076 | 0.3110 | 0.9969 |
| MCF 10A | Etoposide | 0.2907 | 0.3102 | -0.0078 | -0.0447 | 1.3173 | 0.4011 | 0.9962 |
| MCF 10A-H2B-mCherry | Etoposide | 0.4090 | 0.4404 | -0.0002 | -0.0486 | 1.2536 | 0.3585 | 0.9975 |
| MCF 10A | Vorinostat | 0.8751 | 0.9289 | 0.0055 | -0.0446 | 1.4316 | 0.3161 | 0.9978 |
| MCF 10A | Etoposide | 0.2705 | 0.2790 | 0.0077 | -0.0217 | 1.3754 | 0.4012 | 0.9975 |
| MCF 10A-H2B-mCherry | Vorinostat | 1.0062 | 1.0474 | 0.0205 | -0.0332 | 1.6009 | 0.2962 | 0.9969 |
| MCF 10A-H2B-mCherry | Dasatinib | 0.5718 | 0.6948 | 0.0384 | -0.0754 | 0.7208 | 0.3247 | 0.9802 |
| MCF 10A | Trametinib | 0.0031 | 0.0028 | 0.0794 | 0.0633 | 1.3314 | 0.6520 | 0.9917 |
| MCF 10A | Palbociclib | 0.1679 | 0.1316 | 0.0836 | 0.0727 | 0.6451 | 0.4443 | 0.9863 |
| MCF 10A-H2B-mCherry | Neratinib | 0.1788 | 0.1640 | 0.0840 | 0.0624 | 1.5431 | 0.3101 | 0.9972 |
| MCF 10A | Trametinib | 0.0047 | 0.0041 | 0.0903 | 0.0858 | 1.3718 | 0.5949 | 0.9980 |
| MCF 10A | Trametinib | 0.0026 | 0.0021 | 0.1170 | 0.1077 | 1.2989 | 0.6461 | 0.9968 |
| MCF 10A-H2B-mCherry | Trametinib | 0.0050 | 0.0037 | 0.1825 | 0.1771 | 1.5030 | 0.5440 | 0.9983 |