LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 8 of 9: Calculated dose-response metrics for biological replicate 2 - Dataset (ID:20285)

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Cell Small Molecule GR50 GEC50 GRmax GRinf GR Hill Coefficient GR_AOC GR r2
MCF 10A Neratinib 0.2494 0.2269 0.0973 0.0742 1.7025 0.2694 0.9968
MCF 10A Neratinib 0.0854 0.1085 -0.2044 -0.1811 1.2873 0.4415 0.9962
MCF 10A Neratinib 0.0844 0.0786 0.0203 0.0483 1.4159 0.3901 0.9928
MCF 10A-H2B-mCherry Neratinib 0.2974 0.2707 0.0879 0.0936 2.2025 0.2385 0.9931
MCF 10A Dasatinib 0.8353 0.9301 0.0748 -0.0424 0.7571 0.2807 0.9782
MCF 10A Dasatinib 0.0909 0.1074 -0.1824 -0.1422 1.4974 0.5841 0.9871
MCF 10A Dasatinib 0.0810 0.0827 -0.0047 -0.0080 0.7728 0.5320 0.9926
MCF 10A-H2B-mCherry Dasatinib 0.9841 1.2778 0.0635 -0.1135 0.7832 0.2675 0.9758
MCF 10A Palbociclib 1.2755 0.5688 0.2704 0.3116 1.2083 0.2116 0.9514
MCF 10A Palbociclib 0.8350 0.3679 0.2924 0.3584 1.5390 0.2368 0.9554
MCF 10A Palbociclib 0.2045 0.1516 0.1261 0.1792 1.4805 0.4046 0.9595
MCF 10A-H2B-mCherry Palbociclib 0.3909 0.2786 0.1684 0.2278 1.7943 0.3121 0.9603
MCF 10A Taxol 0.0025 0.0030 -0.2458 -0.2136 1.8640 0.6283 0.9980
MCF 10A Taxol 0.0020 0.0027 -0.3381 -0.3108 1.5254 0.6955 0.9958
MCF 10A Taxol 0.0024 0.0025 -0.0912 -0.0354 1.5519 0.5613 0.9895
MCF 10A-H2B-mCherry Taxol 0.0022 0.0028 -0.2538 -0.2399 1.5255 0.6574 0.9975
MCF 10A Trametinib 0.0092 0.0067 0.2162 0.2201 1.8586 0.4582 0.9972
MCF 10A Trametinib 0.0036 0.0035 0.0155 0.0092 1.2589 0.6610 0.9982
MCF 10A Trametinib 0.0028 0.0023 0.1077 0.1244 1.3298 0.6281 0.9950
MCF 10A-H2B-mCherry Trametinib 0.0089 0.0065 0.1990 0.2186 1.8519 0.4587 0.9947
MCF 10A Alpelisib 20.7478 79.3409 0.6862 -0.9999 0.8190 0.0497 0.9948
MCF 10A Alpelisib 4.9885 28.7866 0.3135 -1.0000 0.6268 0.1660 0.9919
MCF 10A Alpelisib 3.9849 5.6167 0.2942 -0.1374 0.7074 0.1770 0.9910
MCF 10A-H2B-mCherry Alpelisib 61.2517 17.9647 0.7853 0.3741 1.1241 0.0285 0.9734
MCF 10A Etoposide 0.2753 0.2974 -0.0085 -0.0513 1.2687 0.4067 0.9974
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