LINCS MCF 10A Common Project: Fixed-time-point sensitivity measures of the MCF 10A breast cell line to 8 small molecule perturbagens. Dataset 7 of 9: Calculated dose-response metrics for biological replicate 1 - Dataset (ID:20284)

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Cell Small Molecule GR50 GEC50 GRmax GRinf GR Hill Coefficient GR_AOC GR r2
MCF 10A Neratinib 0.2035 0.1967 0.0393 0.0275 1.6616 0.2999 0.9954
MCF 10A Neratinib 0.1465 0.1403 0.0391 0.0306 1.4801 0.3367 0.9964
MCF 10A Neratinib 0.0574 0.0601 -0.0843 -0.0304 1.2896 0.4496 0.9941
MCF 10A-H2B-mCherry Neratinib 0.2118 0.2042 0.0390 0.0325 1.8536 0.2897 0.9945
MCF 10A Dasatinib 0.7297 1.0369 0.0657 -0.1269 0.6437 0.3098 0.9753
MCF 10A Dasatinib 0.2352 0.3704 -0.1484 -0.2039 0.7528 0.4459 0.9908
MCF 10A Dasatinib 0.0465 0.0448 0.0027 0.0133 0.7433 0.5793 0.9869
MCF 10A-H2B-mCherry Dasatinib 0.5884 0.7893 -0.0183 -0.1250 0.7592 0.3179 0.9711
MCF 10A Palbociclib 1.3268 0.8000 0.2417 0.1883 0.9336 0.2317 0.9832
MCF 10A Palbociclib 3.7099 1.0978 0.3946 0.3508 0.9929 0.1636 0.9875
MCF 10A Palbociclib 0.1789 0.1367 0.1119 0.1033 0.8605 0.4324 0.9737
MCF 10A-H2B-mCherry Palbociclib 0.5495 0.4072 0.1514 0.1278 0.9849 0.3140 0.9806
MCF 10A Taxol 0.0026 0.0029 -0.1780 -0.1453 1.9905 0.6001 0.9965
MCF 10A Taxol 0.0023 0.0029 -0.3203 -0.2638 1.9596 0.6641 0.9946
MCF 10A Taxol 0.0027 0.0028 -0.0785 -0.0323 1.3129 0.5367 0.9896
MCF 10A-H2B-mCherry Taxol 0.0021 0.0026 -0.2118 -0.1960 1.6063 0.6412 0.9952
MCF 10A Trametinib 0.0091 0.0064 0.2440 0.2439 1.8343 0.4490 0.9983
MCF 10A Trametinib 0.0048 0.0036 0.1623 0.1579 1.3421 0.5592 0.9988
MCF 10A Trametinib 0.0024 0.0021 0.0556 0.0851 1.4625 0.6651 0.9963
MCF 10A-H2B-mCherry Trametinib 0.0077 0.0058 0.1871 0.1974 1.7945 0.4836 0.9944
MCF 10A Alpelisib 19.9680 109.9398 0.6403 -0.9990 0.6437 0.0749 0.9925
MCF 10A Alpelisib 14.6463 76.5784 0.5793 -1.0000 0.6642 0.0853 0.9924
MCF 10A Alpelisib 2.5692 5.3087 0.1991 -0.3002 0.6479 0.2211 0.9896
MCF 10A-H2B-mCherry Alpelisib 19.9827 54.4563 0.7238 -0.9784 1.0813 0.0334 0.9858
MCF 10A Etoposide 0.3116 0.3399 -0.0170 -0.0616 1.3374 0.3965 0.9966
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