Protein levels measured by imaging in BRAF(V600E/D) melanoma cell lines following treatment with Vemurafenib in combination with chromatin-targeting compounds (immunofluorescence dataset 3 of 4) - Dataset (ID:20276)

 Full screen view
Filter results: >>>>
Cell Small Molecule 1 Small Molecule 2 Small Mol 1 Concentration Small Mol 2 Concentration Small Mol Conc Unit Time Point Time Point Unit Replicate Number of Cells Primary Antibody (488) Secondary Antibody (488) Protein Detected (488) Mean Fluorescence Intensity (488) Primary Antibody (647) Secondary Antibody (647) Protein Detected (647) Mean Fluorescence Intensity (647) Plate Name Plate Well
WM-115 Vemurafenib 1.0000
uM
 48
hr
 2 815 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 120.80 NGFR rabbit IgG(H+L) / donkey NGFR 893.83
WM115-A2-rep2
H6
WM-115 Vemurafenib 1.0000
uM
 48
hr
 2 810 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 133.85 NGFR rabbit IgG(H+L) / donkey NGFR 859.67
WM115-A2-rep2
H7
WM-115 Vemurafenib 1.0000
uM
 48
hr
 2 845 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 127.28 NGFR rabbit IgG(H+L) / donkey NGFR 900.40
WM115-A2-rep2
H8
WM-115 Vemurafenib 1.0000
uM
 48
hr
 2 836 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 130.96 NGFR rabbit IgG(H+L) / donkey NGFR 867.95
WM115-A2-rep2
H9
WM-115 Vemurafenib 1.0000
uM
 48
hr
 1 1238 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 135.53 NGFR rabbit IgG(H+L) / donkey NGFR 1143.34
WM115-B1-rep1
A10
WM-115 Vemurafenib 1.0000
uM
 48
hr
 1 1082 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 153.35 NGFR rabbit IgG(H+L) / donkey NGFR 1063.55
WM115-B1-rep1
A11
WM-115 Vemurafenib 1.0000
uM
 48
hr
 1 1290 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 150.40 NGFR rabbit IgG(H+L) / donkey NGFR 1023.32
WM115-B1-rep1
A2
WM-115 Vemurafenib 1.0000
uM
 48
hr
 1 1254 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 156.90 NGFR rabbit IgG(H+L) / donkey NGFR 981.56
WM115-B1-rep1
A3
WM-115 Vemurafenib 1.0000
uM
 48
hr
 1 1219 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 156.46 NGFR rabbit IgG(H+L) / donkey NGFR 1014.83
WM115-B1-rep1
A4
WM-115 Vemurafenib 1.0000
uM
 48
hr
 1 1092 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 136.52 NGFR rabbit IgG(H+L) / donkey NGFR 1059.09
WM115-B1-rep1
A5
WM-115 Vemurafenib 1.0000
uM
 48
hr
 1 1112 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 145.20 NGFR rabbit IgG(H+L) / donkey NGFR 1115.20
WM115-B1-rep1
A6
WM-115 Vemurafenib 1.0000
uM
 48
hr
 1 1157 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 127.07 NGFR rabbit IgG(H+L) / donkey NGFR 983.86
WM115-B1-rep1
A7
WM-115 Vemurafenib 1.0000
uM
 48
hr
 1 1191 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 189.12 NGFR rabbit IgG(H+L) / donkey NGFR 985.32
WM115-B1-rep1
A8
WM-115 Vemurafenib 1.0000
uM
 48
hr
 1 1203 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 142.67 NGFR rabbit IgG(H+L) / donkey NGFR 1034.60
WM115-B1-rep1
A9
WM-115 Vemurafenib Olaparib 1.0000 0.5333
uM
 48
hr
 1 1167 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 137.87 NGFR rabbit IgG(H+L) / donkey NGFR 1037.33
WM115-B1-rep1
B2
WM-115 Vemurafenib Iniparib 1.0000 0.5333
uM
 48
hr
 1 1365 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 134.80 NGFR rabbit IgG(H+L) / donkey NGFR 1019.80
WM115-B1-rep1
B3
WM-115 Vemurafenib CTB 1.0000 0.5333
uM
 48
hr
 1 1430 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 143.37 NGFR rabbit IgG(H+L) / donkey NGFR 993.65
WM115-B1-rep1
B4
WM-115 Vemurafenib Rocilinostat 1.0000 0.5333
uM
 48
hr
 1 1305 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 123.30 NGFR rabbit IgG(H+L) / donkey NGFR 965.10
WM115-B1-rep1
B5
WM-115 Vemurafenib GSK-J1 1.0000 0.5333
uM
 48
hr
 1 1268 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 142.27 NGFR rabbit IgG(H+L) / donkey NGFR 1155.24
WM115-B1-rep1
B6
WM-115 Vemurafenib PFI-1 1.0000 0.5333
uM
 48
hr
 1 1121 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 128.12 NGFR rabbit IgG(H+L) / donkey NGFR 999.98
WM115-B1-rep1
B7
WM-115 Vemurafenib UNC669 1.0000 0.5333
uM
 48
hr
 1 1278 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 156.58 NGFR rabbit IgG(H+L) / donkey NGFR 1084.81
WM115-B1-rep1
B8
WM-115 Vemurafenib Veliparib 1.0000 0.5333
uM
 48
hr
 1 1336 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 145.75 NGFR rabbit IgG(H+L) / donkey NGFR 1058.87
WM115-B1-rep1
C2
WM-115 Vemurafenib Rucaparib 1.0000 0.5333
uM
 48
hr
 1 1363 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 131.98 NGFR rabbit IgG(H+L) / donkey NGFR 1087.96
WM115-B1-rep1
C3
WM-115 Vemurafenib Belinostat 1.0000 0.5333
uM
 48
hr
 1 1138 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 133.07 NGFR rabbit IgG(H+L) / donkey NGFR 352.75
WM115-B1-rep1
C4
WM-115 Vemurafenib Selisistat 1.0000 0.5333
uM
 48
hr
 1 1456 KI-67 / clone 8D5 mouse IgG(H+L) / donkey KI-67 145.36 NGFR rabbit IgG(H+L) / donkey NGFR 1148.05
WM115-B1-rep1
C5